Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988491 | 0.91 | ALDH1A1 (0.49) | NPC1RAB9AUSP2NAMPTLMNA | |
| SCHEMBL9989252 | 0.86 | NPC1 (0.53) | NPC1RAB9AMAPK1LMNAKMT2A | |
| SCHEMBL9989823 | 0.84 | RXRA (0.40) | RAB9ALMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL9989017 | 0.79 | MALT1 (0.53) | — | |
| SCHEMBL9988495 | 0.77 | MALT1 (0.49) | NAMPT | |
| SCHEMBL9988522 | 0.77 | MALT1 (0.50) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9990189 | 0.76 | MALT1 (0.49) | RAB9AKMT2AMEN1TSHRKDM4E | |
| SCHEMBL9988484 | 0.76 | MALT1 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9988478 | 0.76 | MALT1 (0.56) | — | |
| SCHEMBL9988866 | 0.76 | MALT1 (0.49) | LMNAKMT2ATSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |