Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989594 | 0.91 | NPC1 (0.49) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9988457 | 0.86 | PTGS2 (0.44) | ALDH1A1MAPTNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9988469 | 0.85 | RAB9A (0.40) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL9989252 | 0.84 | NPC1 (0.53) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9988617 | 0.81 | MALT1 (0.43) | — | |
| SCHEMBL9988828 | 0.79 | MALT1 (0.45) | MAPTSMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL9988443 | 0.79 | NAMPT (0.44) | ALDH1A1MAPTLMNAKMT2ATSHR | |
| SCHEMBL9989144 | 0.78 | SMN1; SMN2 (0.49) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9988364 | 0.78 | MALT1 (0.49) | KMT2A | |
| SCHEMBL9988979 | 0.77 | ADORA2A (0.43) | ALDH1A1MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |