Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062964 | 0.86 | XDH (0.44) | DHODHMEN1POLBMAPTKMT2A | |
| SCHEMBL9989324 | 0.76 | GABRA1 (0.43) | DHODHMEN1POLBMAPTKMT2A | |
| SCHEMBL9990065 | 0.74 | PTGS2 (0.40) | DHODHMEN1POLBMAPTKMT2A | |
| SCHEMBL12074876 | 0.74 | PTGS2 (0.38) | MEN1MAPTKMT2APTGS2LMNA | |
| SCHEMBL7804618 | 0.73 | S1PR1 (0.40) | DHODHMEN1POLBMAPTKMT2A | |
| SCHEMBL12074872 | 0.73 | GPR84 (0.38) | MEN1MAPTKMT2APPARGPPARA | |
| SCHEMBL9150076 | 0.73 | MEN1 (0.43) | MEN1POLBKMT2ABCHEACHE | |
| SCHEMBL9989326 | 0.72 | TNF (0.42) | DHODHMEN1POLBMAPTKMT2A | |
| SCHEMBL9989089 | 0.70 | ENPP1 (0.42) | CYP2C9 | |
| SCHEMBL4245330 | 0.70 | MEN1 (0.61) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163610-A2 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-29 | — | — | WO | disclosed |