Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064314 | 0.87 | ATM (0.46) | LMNAF2SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL8003710 | 0.85 | PBRM1 (0.59) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL9510637 | 0.83 | PBRM1 (0.57) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL28045479 | 0.82 | PBRM1 (0.55) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL28539853 | 0.82 | PBRM1 (0.55) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL5033580 | 0.82 | PBRM1 (0.55) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29836775 | 0.82 | LOXL2 (0.61) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL13399668 | 0.82 | PBRM1 (0.55) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29071827 | 0.82 | PBRM1 (0.55) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL134170 | 0.82 | LOXL2 (0.61) | PBRM1NPC1MITFLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868135-B2 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | BIOWEST THERAPEUTICS INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| EP-2147925-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2010-01-27 | — | — | EP | disclosed |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-17 | — | — | US | disclosed |
| WO-2008080223-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-10 | — | — | WO | disclosed |
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-25 | — | — | US | disclosed |
| US-7083833-B2 | Photoalignment materials and liquid crystal display fabricated with such photoalignment materials | LG.PHILIPS LCD CO., LTD. (KR) | 2006-08-01 | — | — | US | disclosed |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2005-07-14 | — | — | US | disclosed |
| US-20040219307-A1 | Photoalignment materials and liquid crystal display fabricated with such photoalignment materials | LG DISPLAY CO., LTD. (KR) | 2004-11-04 | — | — | US | disclosed |
| US-6793987-B2 | FOR USE IN FLAT PANEL DISPLAY DEVICES, INCLUDING LIQUID CRYSTAL DISPLAY DEVICES, ARE WIDELY USED IN CELLULAR PHONES, NOTEBOOK COMPUTERS, AND WIDE SCREEN TELEVISIONS | LG.PHILIPS LCD CO., LTD. (KR) | 2004-09-21 | — | — | US | disclosed |
| US-6770335-B2 | FOR USE IN FLAT PANEL DISPLAY DEVICES, INCLUDING LIQUID CRYSTAL DISPLAY DEVICES, ARE WIDELY USED IN CELLULAR PHONES, NOTEBOOK COMPUTERS, AND WIDE SCREEN TELEVISIONS | LG.PHILIPS LCD CO., LTD. (KR) | 2004-08-03 | — | — | US | disclosed |
| US-20020054966-A1 | Photoalignment materials and liquid crystal display fabricated with such photoalignment materials | LG DISPLAY CO., LTD. (KR) | 2002-05-09 | — | — | US | disclosed |
| US-20020054967-A1 | Photoalignment materials and liquid crystal display device and method for fabricating the same with said materials | LG DISPLAY CO., LTD. (KR) | 2002-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | HAVCR2, ADAR, NSUN2 | PBRM1 4746/4885NPC1 83/4885MITF 3498/4885 |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | NRDC, NOD2, NGLY1 | PBRM1 3919/4885NPC1 1821/4885MITF 1546/4885 |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | POLQ, POLI, POLH | PBRM1 738/4885NPC1 2526/4885MITF 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.