Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.54 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637555 | 0.82 | KMT2A (0.58) | ACLYMEN1KMT2AKDM4EPOLB | |
| SCHEMBL28653065 | 0.81 | PFKFB3 (0.48) | ACLYMEN1KMT2AKDM4EPOLB | |
| SCHEMBL21218351 | 0.79 | SLC40A1 (0.53) | GLO1SLC40A1ACLYKDM4EKAT6A | |
| SCHEMBL9997060 | 0.79 | PFKFB3 (0.58) | MEN1KMT2APGRMCL1PFKFB3 | |
| SCHEMBL3983954 | 0.78 | METAP2 (0.72) | GLO1SLC40A1ACLYPGAM1PGR | |
| SCHEMBL9997386 | 0.77 | ALDH1A1 (0.62) | ACLYMEN1KMT2AKDM4EPOLB | |
| SCHEMBL9996881 | 0.77 | ALDH1A1 (0.62) | GLO1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL14075357 | 0.75 | PGR (0.59) | ACLYMEN1KMT2AKDM4EKAT6A | |
| SCHEMBL17538556 | 0.75 | ALDH1A1 (0.63) | GLO1ACLYMEN1KMT2AKDM4E | |
| SCHEMBL28637411 | 0.75 | ACLY (0.55) | ACLYMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |