Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 8/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996879 | 0.80 | KMT2A (0.41) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9997385 | 0.78 | POLB (0.41) | POLBL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL9997382 | 0.75 | CA12 (0.44) | TSHRPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL15259940 | 0.74 | MEP1B (0.46) | MEP1BMMP7TSHRPOLBL3MBTL1 | |
| SCHEMBL9997302 | 0.72 | KAT6A (0.42) | — | |
| SCHEMBL9997528 | 0.70 | KMT2A (0.48) | MEN1KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL9997179 | 0.70 | PTK2B (0.34) | POLBL3MBTL1LMNA | |
| SCHEMBL9997441 | 0.68 | FBP1 (0.39) | — | |
| SCHEMBL12413877 | 0.67 | POLB (0.59) | MEP1BTSHRPOLBL3MBTL1MAPK1 | |
| SCHEMBL6357490 | 0.66 | HSD11B1 (0.40) | CCR2CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |