Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RPA1 | P27694 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997385 | 0.80 | POLB (0.41) | KMT2ASMN1; SMN2GFERALDH1A1LMNA | |
| SCHEMBL9997179 | 0.74 | PTK2B (0.34) | SMN1; SMN2LMNA | |
| SCHEMBL9996879 | 0.71 | KMT2A (0.41) | KMT2AMAPTSMN1; SMN2GFERALDH1A1 | |
| SCHEMBL9997441 | 0.70 | FBP1 (0.39) | — | |
| SCHEMBL9997382 | 0.70 | CA12 (0.44) | KMT2AMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21857831 | 0.68 | GAA (0.48) | KMT2AMAPTALDH1A1 | |
| SCHEMBL9997302 | 0.67 | KAT6A (0.42) | MAPT | |
| SCHEMBL9997528 | 0.66 | KMT2A (0.48) | KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9997338 | 0.66 | MEP1B (0.47) | KMT2AALDH1A1MEP1BLMNA | |
| SCHEMBL264514 | 0.65 | LMNA (0.65) | EDNRBEDNRAKMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |