Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637555 | 0.78 | KMT2A (0.58) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL9996881 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL9997386 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDL3MBTL1HSD17B10 | |
| SCHEMBL9996941 | 0.77 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL21999856 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGD | |
| SCHEMBL9997384 | 0.75 | LMNA (0.67) | ALDH1A1KDM4EHSD17B10SMN1; SMN2TSHR | |
| SCHEMBL29540849 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDL3MBTL1HSD17B10 | |
| SCHEMBL22252162 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDL3MBTL1HSD17B10 | |
| SCHEMBL9997303 | 0.73 | GLO1 (0.54) | KDM4EMEN1KMT2AMAPTPOLB | |
| SCHEMBL6079716 | 0.73 | MEN1 (0.53) | ALDH1A1KDM4EMAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |