RGS17

Regulator of G-protein signaling 17 · Q9UGC6 · RGS17 on Sugi Atlas →

1,289 patent compounds predicted against RGS17, 907 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Sanguinarium (SCHEMBL43290)	1.00	2/20
Sanguinarium (SCHEMBL123241)	1.00	2/20
Sanguinarium (SCHEMBL3222766)	0.97	2/20
Sanguinarium (SCHEMBL8583232)	0.97	2/20
Sanguinarium (SCHEMBL8584009)	0.97	2/20
Sanguinarium (SCHEMBL8937106)	0.97	2/20
Sanguinarium (SCHEMBL454298)	0.88	2/20
Sanguinarium (SCHEMBL9766877)	0.88	2/20
Sanguinarium (SCHEMBL1463519)	0.86	2/20
Sanguinarium (SCHEMBL9405581)	0.84	2/20
Sanguinarium (SCHEMBL9698540)	0.77	2/20
Sanguinarium (SCHEMBL9722574)	0.77	2/20
SCHEMBL10132560	0.76	2/20
Sanguinarium (SCHEMBL9651347)	0.74	2/20
SCHEMBL13170174	0.72	2/20
Sanguinarium (SCHEMBL3488081)	0.71	2/20
Sanguinarium (SCHEMBL9651303)	0.70	2/20
SCHEMBL10132358	0.69	2/20
SCHEMBL14392714	0.67	2/20
Sanguinarium (SCHEMBL10625139)	0.66	2/20

Clinical trials — most relevant to RGS17 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell.	PHASE4	UNKNOWN
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus	PHASE3	UNKNOWN
Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old	PHASE2	ACTIVE_NOT_RECRUITING
GSNOR Phenotyping/GSNO Challenge in Severe Asthma	EARLY_PHASE1	COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Adrenocorticotropic Hormone (ACTH) Stimulation and G Protein	nan	COMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms	nan	COMPLETED
Intravenous Terbutaline in Severe Status Asthmaticus	nan	UNKNOWN
RAFTLIN-1 Levels in Axial Spondyloarthritis and Psoriatic Arthritis	nan	COMPLETED
Thrombin Regulated Platelet Activation	nan	COMPLETED
Effects of Mulberry Juice on Inflammatory Status and Clinical Symptoms in Patients With General Anxiety Disorder	nan	UNKNOWN
Polycystic Ovary Syndrome in Type 1 Diabetes	nan	NOT_YET_RECRUITING
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins.	nan	UNKNOWN
The Application of 68Ga-Pentixafor Alongside 68Ga-FAPI-04 PET/MR for Assessing Primary Aldosteronism.	nan	NOT_YET_RECRUITING
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome	nan	ACTIVE_NOT_RECRUITING
Brain Receptors in Sympathetic Nervous System Regulation	nan	COMPLETED
Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy)	nan	UNKNOWN
Prescribing Asthma Controller Medication According to Gene Status to Improve Quality of Life in Young People With Asthma	nan	COMPLETED
Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation	nan	UNKNOWN
Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity	nan	NOT_YET_RECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Vulvodynia: Identification of Potential Relevant Biomarkers	nan	COMPLETED
Evaluation of Vasopressin in the Vessels of Ovarian Neoplasms	nan	COMPLETED
Defining the Brain Phenotype of Children With Williams Syndrome	nan	RECRUITING
Relationship Between Genes Important in Blood Pressure Regulation and Blood Pressure Therapy in Hypertension	nan	COMPLETED
Inherited Reproductive Disorders	nan	RECRUITING
The Effect of Anti-IL17 on Airway Hyperresponsiveness and Resistance	nan	RECRUITING
Perioperative Plasma Levels of Glycocalyx Markers in Colon Surgery.	nan	UNKNOWN
Effect of Intraperitoneal Bupivacaine with Dexmedotomidine or Fentanyl for Post-Operative Analgesia Following Laparoscopy in Pediatric Patients	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a RGS17 binder may also engage these)

Protein	Name	Similarity
Q9QZB0	—	1.000	Q9QZB0 →
Q9PWA0	—	1.000	Q9PWA0 →
Q9PWA1	—	1.000	Q9PWA1 →
Q6RG78	—	0.997	Q6RG78 →
Q9JL25	—	0.995	Q9JL25 →
P49806	—	0.994	P49806 →
Q99PG4	—	0.994	Q99PG4 →
P49808	—	0.993	P49808 →
O43665	—	0.993	O43665 →
Q4L0E8	—	0.992	Q4L0E8 →
Q9QZB1	—	0.992	Q9QZB1 →
Q3S853	—	0.992	Q3S853 →
P56700	—	0.991	P56700 →
Q08DC7	—	0.991	Q08DC7 →
P34295	—	0.991	P34295 →
P97844	—	0.990	P97844 →
P49802	—	0.989	P49802 →
RGS19	Regulator of G-protein signaling 19	0.989	landscape →
Q9NS28	—	0.989	Q9NS28 →
Q9CQE5	—	0.988	Q9CQE5 →
Q0P5H5	—	0.987	Q0P5H5 →
P41220	—	0.987	P41220 →
Q2KHW7	—	0.987	Q2KHW7 →
Q08116	—	0.987	Q08116 →
Q9CX84	—	0.986	Q9CX84 →
Q5M8L6	—	0.986	Q5M8L6 →
O15539	—	0.986	O15539 →
Q9DDT2	—	0.985	Q9DDT2 →
A1A643	—	0.985	A1A643 →
P25799	—	0.985	P25799 →