Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | YWHAB | P31946 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453756 | 0.84 | RAB9A (0.47) | ALDH1A1HPGDKMT2AMEN1NCOR2 | |
| SCHEMBL9770486 | 0.79 | PTPN1 (0.78) | ESR1YWHABPDK1PTPN1ALDH1A1 | |
| SCHEMBL6613422 | 0.76 | PKM (0.43) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL902241 | 0.75 | ALOX15 (0.53) | PTPN1ALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL9265091 | 0.74 | HPGD (0.81) | ESR1YWHABPDK1PTPN1ALDH1A1 | |
| SCHEMBL6956890 | 0.74 | SPR (0.70) | ESR1YWHABPDK1PTPN1ALDH1A1 | |
| SCHEMBL17117361 | 0.73 | ESR1 (0.56) | ESR1YWHABPDK1PTPN1ALDH1A1 | |
| SCHEMBL7579636 | 0.73 | RAB9A (0.55) | ALDH1A1HPGDSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL11359120 | 0.73 | ESR1 (0.56) | ESR1YWHABPDK1PTPN1ALDH1A1 | |
| SCHEMBL4737461 | 0.72 | MEN1 (0.78) | ESR1YWHABPDK1PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010180-A | Printing, dyeing | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |