SCHEMBL10014046

SCHEMBL10014046

CC1(C)c2ccccc2-c2cc3c(cc21)c1ccccc1n3-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ ATM Q13315 1/20 0.50
▸ PGR P06401 6/20 0.38
▸ MAPK8 P45983 2/20 0.34
▸ HDAC4 P56524 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ HPGD P15428 2/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ KMT2A Q03164 3/20 0.31
▸ IL1R1 P14778 1/20 0.31
▸ KDR P35968 1/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ MAPT P10636 2/20 0.31
▸ HTT P42858 2/20 0.31
▸ MAPK9 P45984 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18381859 0.99 KDM4E (0.49) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL17245623 0.96 KDM4E (0.43) KDM4EL3MBTL1ATMPGRHDAC4
SCHEMBL17245591 0.95 KDM4E (0.45) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL783308 0.94 KDM4E (0.50) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL25147207 0.94 KDM4E (0.56) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL16919334 0.94 PGR (0.42) KDM4EL3MBTL1ATMPGRALDH1A1
SCHEMBL15338025 0.94 L3MBTL1 (0.44) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL2609844 0.94 L3MBTL1 (0.44) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL18381855 0.93 KDM4E (0.49) KDM4EL3MBTL1ATMPGRMAPK8
SCHEMBL17245626 0.93 KDM4E (0.41) KDM4EL3MBTL1ATMPGRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-30 — — US disclosed
EP-4019503-A2 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-29 — — EP disclosed
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2021-05-20 — — US disclosed
WO-2021074106-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-22 — — WO disclosed
US-20210020850-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-01-21 — — US disclosed
US-20200399251-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-12-24 — — US disclosed
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 — — US disclosed
US-20200212306-A1 QUANTUM DOT ELECTROLUMINESCENCE DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-07-02 — — US disclosed
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 — — US disclosed
EP-3138858-B1 AMINO FLUORENE POLYMER AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2019-10-30 — — EP disclosed
US-20150380662-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 — — US disclosed
US-20150380662-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
US-20150318510-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD (KR) 2015-11-05 — — US disclosed
US-20150318510-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD (KR) 2015-11-05 — — US disclosed
US-20140034942-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2014-02-06 — — US disclosed
US-20140034942-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2014-02-06 — — US disclosed
US-20120018717-A1 ORGANIC ELECTRONIC DEVICE, COMPOUNDS FOR SAME, AND TERMINAL DUKSAN HIGH METAL CO., LTD. (KR) 2012-01-26 — — US disclosed
US-20120018717-A1 ORGANIC ELECTRONIC DEVICE, COMPOUNDS FOR SAME, AND TERMINAL DUKSAN HIGH METAL CO., LTD. (KR) 2012-01-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200399251-A1 COMPOUNDS FOR ELECTRONIC DEVICES PNMT, SLC18A2, SLC18A3 KDM4E 2418/4885L3MBTL1 3816/4885ATM 1768/4885
US-20210147442-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL, AND APPLICATION THEREOF ILK, OSTC, LEF1 KDM4E 3975/4885L3MBTL1 1968/4885ATM 1417/4885
US-20210020850-A1 COMPOUNDS FOR ELECTRONIC DEVICES SLC1A2, PNMT, SLC18A2 KDM4E 2030/4885L3MBTL1 3913/4885ATM 2283/4885
US-20120018717-A1 ORGANIC ELECTRONIC DEVICE, COMPOUNDS FOR SAME, AND TERMINAL OR10J3, OR51E2, ESR1 KDM4E 648/4885L3MBTL1 1048/4885ATM 3834/4885
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME EML4, STOM, GJB2 KDM4E 1381/4885L3MBTL1 1734/4885ATM 4302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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