SCHEMBL10014869

SCHEMBL10014869

Cn1c2ccccc2n(C)c2cc3c(cc21)n(C)c1ccccc1n3C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.60
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KIF11 P52732 1/20 0.42
NQO2 P16083 1/20 0.41
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
BRD4 O60885 1/20 0.41
BRPF1 P55201 1/20 0.41
KAT2B Q92831 1/20 0.41
BRD9 Q9H8M2 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889048 0.76 GPR3 (0.76) GPR3KDM4EALDH1A1MAPTKMT2A
SCHEMBL29461528 0.75 GPR3 (1.00) GPR3KDM4EALDH1A1MAPTKMT2A
SCHEMBL3233843 0.75 GPR3 (0.52) GPR3KDM4EALDH1A1MAPTKMT2A
SCHEMBL29321 0.75 GPR3 (1.00) GPR3KDM4EALDH1A1MAPTKMT2A
SCHEMBL24052039 0.73 HTT (0.52) GPR3MAPTKMT2AHTTSMN1; SMN2
Hydrochloric Acid SCHEMBL31174327 0.73 GPR3 (0.94) GPR3KDM4EALDH1A1MAPTKMT2A
SCHEMBL31093975 0.73 GABRA5 (0.55) GPR3KDM4EALDH1A1KMT2AHPGD
SCHEMBL29798837 0.73 CYP1A2 (0.55) GPR3KDM4EALDH1A1KMT2AMEN1
SCHEMBL18381839 0.73 GPR3 (0.94) GPR3KDM4EALDH1A1MAPTKMT2A
SCHEMBL1278798 0.73 GABRA5 (0.55) GPR3KDM4EALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334384-B2 Process for preparing tetrahydrotetraazapentacenes and derivatives XEROX CORPORATION (US) 2012-12-18 US disclosed
US-8334384-B2 Process for preparing tetrahydrotetraazapentacenes and derivatives XEROX CORPORATION (US) 2012-12-18 US disclosed
US-8283659-B2 Tetrahydrotetraazapentacenes in thin-film transistors XEROX CORPORATION (US) 2012-10-09 US disclosed
US-8283659-B2 Tetrahydrotetraazapentacenes in thin-film transistors XEROX CORPORATION (US) 2012-10-09 US disclosed
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS XEROX CORPORATION (US) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS CYP4Z1, TCF4, TERT GPR3 3384/4885KDM4E 582/4885ALDH1A1 689/4885
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES DHPS, TBXA2R, DHRS9 GPR3 2430/4885KDM4E 691/4885ALDH1A1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.