SCHEMBL10026007

SCHEMBL10026007

CC(C)(C)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.72
▸ L3MBTL1 Q9Y468 1/20 0.72
▸ MEN1 O00255 2/20 0.60
▸ POLB P06746 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ ALPL P05186 1/20 0.60
▸ ALPI P09923 1/20 0.60
▸ ALPG P10696 1/20 0.60
▸ ATM Q13315 1/20 0.58
▸ PLEC Q15149 1/20 0.58
▸ CA9 Q16790 15/20 0.56
▸ CA1 P00915 13/20 0.56
▸ CA2 P00918 13/20 0.56
▸ DNASE1L3 Q13609 1/20 0.54
▸ PRMT1 Q99873 1/20 0.54
▸ CA12 O43570 5/20 0.54
▸ CA14 Q9ULX7 2/20 0.51
▸ CA7 P43166 2/20 0.49
▸ ESR1 P03372 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19370241 0.93 USP2 (0.64) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20256559 0.87 USP2 (0.58) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20411331 0.86 USP2 (0.55) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL10098714 0.86 USP2 (0.76) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL19449068 0.85 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL1437042 0.84 USP2 (0.78) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20254033 0.84 USP2 (0.77) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL173061 0.84 USP2 (0.73) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL23225857 0.84 USP2 (0.67) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20990646 0.84 USP2 (0.67) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS SONY GROUP CORP (JP) 2024-06-27 — — US disclosed
US-12018159-B2 Ultra bright dimeric or polymeric dyes and methods for preparation of the same Sony Group Corporation (JP) 2024-06-25 — — US disclosed
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy THE JOHNS HOPKINS UNIVERSTY (US) 2024-02-27 — — US disclosed
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy THE JOHNS HOPKINS UNIVERSTY (US) 2024-02-27 — — US disclosed
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
US-20230364274-A1 IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING FIBROBLAST-ACTIVATION PROTEIN-ALPHA (FAP-ALPHA) THE JOHNS HOPKINS UNIVERSTY 2023-11-16 — — US disclosed
US-20230364274-A1 IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING FIBROBLAST-ACTIVATION PROTEIN-ALPHA (FAP-ALPHA) THE JOHNS HOPKINS UNIVERSTY 2023-11-16 — — US disclosed
US-20230348405-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF THE JOHNS HOPKINS UNIVERSTY 2023-11-02 — — US disclosed
US-20230348405-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF THE JOHNS HOPKINS UNIVERSTY 2023-11-02 — — US disclosed
US-11661402-B2 PSMA-targeting compounds and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2023-05-30 — — US disclosed
US-20170333576-A1 NEW SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY THE JOHNS HOPKINS UNIVERSITY (US) 2017-11-23 — — US disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed
US-9776977-B2 PSMA-targeting compounds and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2017-10-03 — — US disclosed
US-9776977-B2 PSMA-targeting compounds and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2017-10-03 — — US disclosed
US-9562023-B2 Dipeptide mimics, libraries combining two dipeptide mimics with a third group, and methods for production thereof Burgess, Kevin (US) 2017-02-07 — — US disclosed
US-9056841-B2 PSMA-targeting compounds and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2015-06-16 — — US disclosed
US-20150104387-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2015-04-16 — — US disclosed
US-20120009121-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2012-01-12 — — US disclosed
US-20120009121-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2012-01-12 — — US disclosed
US-20090156825-A1 Fluorescent compounds that bind to histone deacetylase MERCK SHARP & DOHME CORP. 2009-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120009121-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF FOLH1, KLK3, PSMA2 USP2 3252/4885L3MBTL1 2898/4885MEN1 190/4885
US-20230348405-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF KLK3, FOLH1, SPR USP2 3285/4885L3MBTL1 4225/4885MEN1 763/4885
US-20090156825-A1 Fluorescent compounds that bind to histone deacetylase HDAC1, HDAC3, HDAC11 USP2 2116/4885L3MBTL1 1410/4885MEN1 3684/4885
US-20150104387-A1 PSMA-TARGETING COMPOUNDS AND USES THEREOF FOLH1, KLK3, PSMA2 USP2 3252/4885L3MBTL1 2898/4885MEN1 190/4885
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy FOLH1, PSMA3, PSMA7 USP2 569/4885L3MBTL1 2409/4885MEN1 844/4885
US-20230364274-A1 IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING FIBROBLAST-ACTIVATION PROTEIN-ALPHA (FAP-ALPHA) FAP, FIBP, FGFR1 USP2 2209/4885L3MBTL1 4133/4885MEN1 1172/4885
US-11661402-B2 PSMA-targeting compounds and uses thereof KLK3, FOLH1, SPR USP2 3285/4885L3MBTL1 4225/4885MEN1 763/4885
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS OPRM1, CHRM1, TUBB3 USP2 3217/4885L3MBTL1 444/4885MEN1 371/4885
US-20170333576-A1 NEW SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY FOLH1, PSMA3, PSMA7 USP2 400/4885L3MBTL1 2706/4885MEN1 1001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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