Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | LOX | P28300 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14233714 | 0.87 | L3MBTL1 (0.63) | SMN1; SMN2NPC1RAB9AROCK2ALDH1A1 | |
| SCHEMBL18718023 | 0.84 | SMN1; SMN2 (0.72) | MRGPRX4SMN1; SMN2NPC1RAB9AROCK2 | |
| SCHEMBL2056391 | 0.84 | HPGD (0.57) | MRGPRX4HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23471233 | 0.84 | MRGPRX4 (0.60) | MRGPRX4HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8284791 | 0.84 | HPGD (0.57) | MRGPRX4HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21015600 | 0.84 | MRGPRX4 (0.54) | MRGPRX4HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1690502 | 0.83 | RAB9A (0.68) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19634293 | 0.83 | LOXL2 (0.65) | MRGPRX4HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21015342 | 0.83 | ROCK2 (0.54) | MRGPRX4HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17032313 | 0.82 | CNR2 (0.48) | SMN1; SMN2NPC1RAB9AROCK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022040-A1 | ANTIMICROBIALS | AMPLYX PHARMACEUTICALS, INC. | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022040-A1 | ANTIMICROBIALS | PAM, MPO, OXA1L | MRGPRX4 3081/4885HPGD 536/4885SMN1; SMN2 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.