SCHEMBL10028081

SCHEMBL10028081

c1ccc(-c2ccccc2-c2cc3ccc4oc5cc(-c6ccccc6-c6ccccc6)cc6ccc7oc(c2)c3c4-c7c65)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 4/20 0.39
WEE1 P30291 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MAOB P27338 3/20 0.37
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 2/20 0.37
NPC1 O15118 3/20 0.36
KMT2A Q03164 2/20 0.36
MIF P14174 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
FYN P06241 1/20 0.36
MAPK3 P27361 1/20 0.36
AHR P35869 1/20 0.36
PAX8 Q06710 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
MAP1LC3B Q9GZQ8 1/20 0.35
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
PLG P00747 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028087 0.88 PGR (0.46) PGRWEE1KDM4EMAOBALDH1A1
SCHEMBL10028082 0.84 CTSD (0.40) KDM4EALDH1A1RAB9ANPC1KMT2A
SCHEMBL10028088 0.83 MEN1 (0.40) KDM4EMAOBALDH1A1RAB9ANPC1
SCHEMBL10028197 0.80 AHR (0.38) KDM4EALDH1A1RAB9ANPC1KMT2A
SCHEMBL10028085 0.78 ESR1 (0.43) PGRKDM4EALDH1A1RAB9ANPC1
SCHEMBL10028189 0.77 CYP1A2 (0.36) PGRKDM4EMAOBALDH1A1KMT2A
SCHEMBL10028145 0.77 WEE1 (0.40) PGRWEE1KDM4EMAOBALDH1A1
SCHEMBL10028086 0.77 CYP1A2 (0.37) KDM4EALDH1A1KMT2ACYP1A1CYP1A2
SCHEMBL10028089 0.77 AHR (0.37) WEE1RAB9ANPC1CYP1A1CYP1A2
SCHEMBL10028196 0.77 MAOA (0.38) MAOBALDH1A1KMT2ACYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046915-B1 NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-12-02 EP disclosed
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed
WO-2008011964-A1 NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2008-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, SOD1, SLC40A1 PGR 2037/4885WEE1 1685/4885KDM4E 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.