SCHEMBL10028086

SCHEMBL10028086

Cc1ccc(-c2cc3ccc4oc5cc(-c6ccc(C)c7ccccc67)cc6ccc7oc(c2)c3c4-c7c65)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.37
ALDH1A1 P00352 5/20 0.32
ABCG2 Q9UNQ0 4/20 0.32
MAPT P10636 3/20 0.32
AHR P35869 3/20 0.32
FYN P06241 2/20 0.32
CYP1A1 P04798 1/20 0.32
MAPK3 P27361 1/20 0.32
PAX8 Q06710 1/20 0.32
LCK P06239 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ACHE P22303 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDM4E B2RXH2 2/20 0.32
PABPC1 P11940 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2A6 P11509 2/20 0.32
TSHR P16473 2/20 0.32
PRKDC P78527 2/20 0.32
HNF4A P41235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028197 0.85 AHR (0.38) CYP1A2ALDH1A1ABCG2MAPTAHR
SCHEMBL10028082 0.84 CTSD (0.40) CYP1A2ALDH1A1MAPTLCKKDM4E
SCHEMBL10028089 0.83 AHR (0.37) CYP1A2ABCG2AHRFYNCYP1A1
SCHEMBL10028088 0.82 MEN1 (0.40) CYP1A2ALDH1A1ABCG2MAPTAHR
SCHEMBL10028196 0.80 MAOA (0.38) CYP1A2ALDH1A1ABCG2MAPTAHR
SCHEMBL12203293 0.79 CYP1A2 (0.39) CYP1A2ALDH1A1ABCG2AHRFYN
SCHEMBL10028081 0.77 PGR (0.39) CYP1A2ALDH1A1ABCG2AHRFYN
SCHEMBL10028092 0.77 ACVR1 (0.41) CYP1A2ALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL10028108 0.77 CYP1A2 (0.46) CYP1A2ALDH1A1MAPTACHEKDM4E
SCHEMBL10028083 0.75 ALDH1A1 (0.33) CYP1A2ALDH1A1MAPTAHRADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046915-B1 NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-12-02 EP disclosed
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-8114531-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100013381-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, SOD1, SLC40A1 CYP1A2 1150/4885ALDH1A1 220/4885ABCG2 1291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.