Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033000 | 0.83 | KDM1A (0.44) | CFTRSLC6A4SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL1709467 | 0.73 | TACR1 (0.41) | SLC6A4KMT2AMEN1TACR1 | |
| SCHEMBL10032999 | 0.71 | SCN9A (0.43) | — | |
| SCHEMBL10033002 | 0.67 | SLC6A2 (0.37) | SLC6A4ALDH1A1KDM4ETACR1POLB | |
| SCHEMBL10033123 | 0.66 | PSEN1 (0.41) | TACR1TRPM8 | |
| SCHEMBL9166296 | 0.66 | POLB (0.40) | TACR1POLB | |
| SCHEMBL1709505 | 0.65 | HDAC4 (0.40) | SLC6A4KMT2AMEN1ALDH1A1TACR1 | |
| SCHEMBL1709388 | 0.64 | MAOA (0.45) | TACR1 | |
| SCHEMBL6239112 | 0.64 | KDM4E (0.55) | SMN1; SMN2RAB9AKMT2ANPC1MEN1 | |
| SCHEMBL10033003 | 0.64 | EPHX2 (0.45) | SMN1; SMN2RAB9AKMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |