Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709386 | 0.86 | MAOA (0.48) | MAOAKDM1AMAOBTACR1 | |
| SCHEMBL1709387 | 0.83 | SSTR3 (0.44) | MAOAKDM1AMAOB | |
| SCHEMBL10033000 | 0.81 | KDM1A (0.44) | MAOAKDM1AMAOBTACR1HCRTR1 | |
| SCHEMBL1709392 | 0.81 | MAOA (0.44) | MAOAKDM1AMAOBTACR1KCNH2 | |
| SCHEMBL1709391 | 0.77 | SSTR3 (0.46) | MAOAKDM1AMAOBTACR1 | |
| SCHEMBL10033123 | 0.69 | PSEN1 (0.41) | HDAC4TACR1HRH3CETP | |
| SCHEMBL1709505 | 0.68 | HDAC4 (0.40) | MAOAKDM1AMAOBHDAC4TACR1 | |
| SCHEMBL10032829 | 0.66 | FFAR1 (0.41) | TACR1HCRTR1 | |
| SCHEMBL11433837 | 0.66 | ALDH1A1 (0.40) | — | |
| SCHEMBL11433840 | 0.66 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |