Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.41 |
| ▸ | AGER | Q15109 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 2/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033002 | 0.86 | SLC6A2 (0.37) | TACR1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL1709391 | 0.79 | SSTR3 (0.46) | TACR1 | |
| SCHEMBL10032999 | 0.79 | SCN9A (0.43) | UBE2MDCUN1D1 | |
| SCHEMBL1709386 | 0.78 | MAOA (0.48) | TACR1 | |
| SCHEMBL10033123 | 0.76 | PSEN1 (0.41) | TACR1 | |
| SCHEMBL1709387 | 0.75 | SSTR3 (0.44) | AGERMTNR1ASLC6A4 | |
| SCHEMBL1709392 | 0.75 | MAOA (0.44) | TACR1KCNH2 | |
| SCHEMBL10033174 | 0.73 | CFTR (0.41) | TACR1MEN1KMT2ASLC6A4 | |
| SCHEMBL9164285 | 0.70 | TACR1 (0.79) | TACR1 | |
| SCHEMBL1709405 | 0.70 | TACR1 (0.38) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |