Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032838 | 0.84 | TP53 (0.40) | L3MBTL1TDP1POLBMEN1KMT2A | |
| SCHEMBL10033115 | 0.83 | MDM2 (0.43) | L3MBTL1TP53 | |
| SCHEMBL10033179 | 0.82 | ALDH1A1 (0.40) | L3MBTL1TDP1ALDH1A1CYP1A2ESR1 | |
| SCHEMBL1709437 | 0.79 | PTGES (0.37) | TDP1POLBKMT2ATAS2R14TP53 | |
| SCHEMBL1709417 | 0.79 | DPP4 (0.42) | L3MBTL1POLBTSHRDPP4MEN1 | |
| SCHEMBL10033105 | 0.79 | TDP1 (0.36) | L3MBTL1TDP1POLBALDH1A1 | |
| SCHEMBL1709421 | 0.78 | L3MBTL1 (0.38) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL10032840 | 0.77 | L3MBTL1 (0.37) | L3MBTL1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL10033108 | 0.77 | L3MBTL1 (0.37) | L3MBTL1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1709371 | 0.72 | MEN1 (0.43) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |