Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 16/20 | 0.43 |
| ▸ | TP53 | P04637 | 13/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033105 | 0.89 | TDP1 (0.36) | L3MBTL1 | |
| SCHEMBL10032838 | 0.88 | TP53 (0.40) | MDM2TP53L3MBTL1 | |
| SCHEMBL1709421 | 0.86 | L3MBTL1 (0.38) | MDM2TP53L3MBTL1 | |
| SCHEMBL10033176 | 0.83 | L3MBTL1 (0.41) | TP53L3MBTL1 | |
| SCHEMBL1709413 | 0.82 | MDM2 (0.41) | MDM2TP53EPHX2 | |
| SCHEMBL10033108 | 0.82 | L3MBTL1 (0.37) | L3MBTL1 | |
| SCHEMBL10032840 | 0.82 | L3MBTL1 (0.37) | L3MBTL1 | |
| SCHEMBL1709437 | 0.82 | PTGES (0.37) | TP53 | |
| SCHEMBL1709371 | 0.77 | MEN1 (0.43) | MDM2TP53 | |
| SCHEMBL10032827 | 0.74 | GPR88 (0.42) | TP53EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |