Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032838 | 0.89 | TP53 (0.40) | TAS2R14TDP1KMT2APOLBTP53 | |
| SCHEMBL1709421 | 0.84 | L3MBTL1 (0.38) | TDP1KMT2ATP53 | |
| SCHEMBL10032840 | 0.82 | L3MBTL1 (0.37) | TDP1KMT2A | |
| SCHEMBL10033108 | 0.82 | L3MBTL1 (0.37) | TDP1KMT2A | |
| SCHEMBL10033105 | 0.82 | TDP1 (0.36) | TDP1POLB | |
| SCHEMBL10033115 | 0.82 | MDM2 (0.43) | TP53 | |
| SCHEMBL10033176 | 0.79 | L3MBTL1 (0.41) | TAS2R14TDP1KMT2APOLBTP53 | |
| SCHEMBL10032973 | 0.77 | SIGMAR1 (0.38) | TDP1KMT2APOLBTP53 | |
| SCHEMBL1709371 | 0.77 | MEN1 (0.43) | NPSR1KMT2ATP53 | |
| SCHEMBL10032827 | 0.76 | GPR88 (0.42) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |