SCHEMBL10040402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15782652	0.84	MAPT (0.44)	TDP1MAPTHPGDAPPTHRB
	SCHEMBL9359137	0.84	TRPV1 (0.52)	TDP1MAPTNPC1RAB9AMEN1
	SCHEMBL10040372	0.83	TDP1 (0.44)	TDP1MAPTHPGDTHRBTSHR
	SCHEMBL11737076	0.81	TDP1 (0.51)	TDP1MAPTHPGDNPC1RAB9A
	SCHEMBL6738921	0.81	IDO1 (0.56)	RXFP1IDO1
	SCHEMBL10040411	0.80	TDP1 (0.42)	TDP1NPC1RAB9ABTKMEN1
	SCHEMBL13588235	0.78	NPC1 (0.47)	TDP1MAPTHPGDTHRBNPC1
	SCHEMBL224821	0.76	GAA (0.56)	TDP1MAPTHPGDTSHRHSD17B10
	SCHEMBL29366694	0.76	GAA (0.56)	TDP1MAPTHPGDTSHRHSD17B10
	SCHEMBL10040396	0.76	TDP1 (0.44)	TDP1MAPTNPC1RAB9ABTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.