Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22259605 | 0.94 | LRRK2 (0.55) | ALDH1A1HPGDSMN1; SMN2PARP10PARP4 | |
| SCHEMBL1004649 | 0.87 | ALDH1A1 (0.73) | ALDH1A1HPGDSMN1; SMN2KMT2AMAPT | |
| Nonane SCHEMBL28429388 | 0.87 | MEN1 (0.54) | ALDH1A1HPGDSMN1; SMN2PARP10KMT2A | |
| Terephthalamide SCHEMBL27683041 | 0.85 | PARP10 (0.58) | ALDH1A1PARP10PARP4PARP1CA2 | |
| SCHEMBL8881536 | 0.81 | LCK (0.58) | ALDH1A1HPGDSMN1; SMN2PARP10PARP4 | |
| SCHEMBL354426 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2PARP10KMT2A | |
| SCHEMBL10626283 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2KMT2AMAPT | |
| Terephthalamide SCHEMBL23774 | 0.79 | PARP1 (0.71) | ALDH1A1SMN1; SMN2PARP10PARP4PARP1 | |
| SCHEMBL128134 | 0.79 | PARP1 (0.57) | PARP10PARP1PARP2KMT2APARP15 | |
| SCHEMBL29562303 | 0.79 | PARP1 (0.57) | PARP10PARP1PARP2KMT2APARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651988-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | ExxonMobil Technology and Engineering Company (US) | 2025-11-26 | — | — | EP | claimed |
| US-12344623-B2 | Thiazolopyridine derivatives as adenosine receptor antagonists | DOMAIN THERAPEUTICS SA (FR) | 2025-07-01 | — | — | US | claimed |
| CN-118931094-A | GTRB polymer composite sole material and manufacturing method of customized sole | 东莞市永铠运动用品有限公司 | 2024-11-12 | — | — | CN | claimed |
| WO-2024155562-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | ExxonMobil Technology and Engineering Company (US) | 2024-07-25 | — | — | WO | claimed |
| CN-118240323-A | Antibacterial fiber sponge material and preparation method thereof | 扬州中天海绵有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118240387-A | Mildew-proof sponge material and preparation method thereof | 扬州中天海绵有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-116442618-A | Decorative board and manufacturing method thereof | 财纳福诺木业(中国)有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-112574567-B | High-strength organic silicon foam plastic and preparation method thereof | 漳州普瑞邦节能科技有限公司 | 2022-11-22 | — | — | CN | claimed |
| US-20220306588-A1 | BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-09-29 | — | — | US | claimed |
| US-11453647-B2 | Benzimidazole derivatives as adenosine receptor antagonists | MERCK PATENT GMBH (DE) | 2022-09-27 | — | — | US | claimed |
| US-8222248-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-07-17 | — | — | US | claimed |
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-29 | — | — | US | claimed |
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-17 | — | — | US | claimed |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | DING QINGJIE | 2010-03-25 | — | — | US | claimed |
| EP-2074089-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-07-01 | — | — | EP | claimed |
| WO-2008048991-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-04-24 | — | — | WO | claimed |
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-12-07 | — | — | US | claimed |
| EP-0138265-B1 | PROCESS FOR THE PRODUCTION OF EXPANDED RETICULATED POLYETHYLENE | AGIP PETROLI S.p.A. (IT) | 1989-04-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344623-B2 | Thiazolopyridine derivatives as adenosine receptor antagonists | ADORA1, ADORA2A, ADORA3 | ALDH1A1 233/4885HPGD 596/4885SMN1; SMN2 4508/4885 |
| US-20220306588-A1 | BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | ADORA1, ADORA2A, ADORA3 | ALDH1A1 1065/4885HPGD 2089/4885SMN1; SMN2 4438/4885 |
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | ALDH1A1 3894/4885HPGD 635/4885SMN1; SMN2 3033/4885 |
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | ARG2, CCNY, PYCR1 | ALDH1A1 2027/4885HPGD 2440/4885SMN1; SMN2 2109/4885 |
| US-11453647-B2 | Benzimidazole derivatives as adenosine receptor antagonists | ADORA1, ADORA2A, ADORA3 | ALDH1A1 617/4885HPGD 1187/4885SMN1; SMN2 4217/4885 |
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | ALDH1A1 3894/4885HPGD 635/4885SMN1; SMN2 3033/4885 |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | ALDH1A1 1278/4885HPGD 3765/4885SMN1; SMN2 4705/4885 |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | ARG2, CCNY, PYCR1 | ALDH1A1 2027/4885HPGD 2440/4885SMN1; SMN2 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.