Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | AGER | Q15109 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10042987 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL10042805 | 0.71 | LMNA (0.74) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL16109738 | 0.66 | HDAC1 (0.65) | ALDH1A1MEN1KMT2ANPSR1HDAC1 | |
| SCHEMBL5645455 | 0.64 | NSD2 (0.67) | MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL12231196 | 0.63 | LIMK2 (0.52) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL29190232 | 0.62 | HDAC1 (0.61) | ALDH1A1LMNAMEN1KMT2AHDAC1 | |
| SCHEMBL569976 | 0.62 | ALDH1A1 (0.82) | ALDH1A1LMNACTSSCTSLMEN1 | |
| SCHEMBL1500765 | 0.61 | BCL2 (0.60) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL30482165 | 0.61 | TDP1 (0.49) | ALDH1A1LMNAAGERMEN1KMT2A | |
| SCHEMBL3640312 | 0.61 | HCRTR1 (0.57) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018932-A2 | COMPOUNDS AND COMPOSITIONS FOR MITIGATING TISSUE DAMAGE AND LETHALITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-09 | — | — | WO | disclosed |