Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13573476 | 0.98 | CHRM2 (0.60) | CHRM2PAOXNFKB1CYP2D6KDM4A | |
| SCHEMBL10044468 | 0.98 | CHRM2 (0.60) | CHRM2PAOXNFKB1CYP2D6KDM4A | |
| SCHEMBL10044463 | 0.93 | CHRM2 (0.46) | CHRM2PAOXNFKB1CYP2D6LMNA | |
| SCHEMBL4285941 | 0.87 | CHRM2 (0.56) | CHRM2PAOXNFKB1CYP2D6KDM4A | |
| SCHEMBL8087943 | 0.84 | — | — | |
| SCHEMBL16299313 | 0.84 | CHRM2 (0.44) | CHRM2PAOXKDM4AHIF1ATET2 | |
| SCHEMBL24112603 | 0.83 | CHRM2 (0.56) | CHRM2PAOXNFKB1CYP2D6LMNA | |
| Ammonia Solution, Strong SCHEMBL27395832 | 0.81 | CHRM2 (0.54) | CHRM2PAOXNFKB1CYP2D6LMNA | |
| SCHEMBL14064830 | 0.80 | GGPS1 (0.47) | KDM4AALDH1A1GGPS1FDPSAGTR1 | |
| SCHEMBL16560407 | 0.80 | PAOX (0.33) | CHRM2PAOXKDM4ESMN1; SMN2GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4170347-A1 | GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS | 3B Pharmaceuticals GmbH (DE) | 2023-04-26 | — | — | EP | disclosed |
| US-20160219880-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NEW YORK UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| US-9364449-B2 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NEW YORK UNIVERSITY (US) | 2016-06-14 | — | — | US | disclosed |
| US-9364449-B2 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NEW YORK UNIVERSITY (US) | 2016-06-14 | — | — | US | disclosed |
| US-9315548-B2 | Peptoid oligomers, pharmaceutical compositions and methods of using the same | NEW YORK UNIVERSITY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150011465-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NEW YORK UNIVERSITY | 2015-01-08 | — | — | US | disclosed |
| US-20140274916-A1 | CYCLIC PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NATIONAL SCIENCE FOUNDATION | 2014-09-18 | — | — | US | disclosed |
| US-20140256639-A1 | PEPTOID NEUTRALIZING AGENTS | UNIV CALIFORNIA (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256638-A1 | PEPTOID NEUTRALIZING AGENTS | UNIV CALIFORNIA (US) | 2014-09-11 | — | — | US | disclosed |
| US-8828413-B2 | Peptoid oligomers, pharmaceutical compositions and methods of using the same | NEW YORK UNIVERSITY (US) | 2014-09-09 | — | — | US | disclosed |
| US-8357654-B2 | Multimeric CD40 ligands, method for preparing same and use thereof for preparing drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-22 | — | — | US | disclosed |
| US-20120015883-A1 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-01-19 | — | — | US | disclosed |
| US-20120015883-A1 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-01-19 | — | — | US | disclosed |
| WO-2011156003-A2 | PEPTOID AND SYNTHETIC OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2011-12-15 | — | — | WO | disclosed |
| US-20100183642-A1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-07-22 | — | — | US | disclosed |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-03 | — | — | US | disclosed |
| US-20100069308-A1 | Surfaces containing antibacterial polymers | CHORNY IIYA | 2010-03-18 | — | — | US | disclosed |
| WO-2008110695-A1 | NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011465-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NOD2, VIP, NOD1 | CHRM2 4400/4885PAOX 103/4885NFKB1 679/4885 |
| US-20160219880-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NOD2, VIP, NOD1 | CHRM2 4400/4885PAOX 103/4885NFKB1 679/4885 |
| US-20120015883-A1 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | APP, IAPP, PSEN1 | CHRM2 2174/4885PAOX 395/4885NFKB1 1061/4885 |
| US-20100183642-A1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CD40, CD40LG, TNFSF10 | CHRM2 196/4885PAOX 1593/4885NFKB1 609/4885 |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | TNFRSF1A, TNFRSF9, CD40 | CHRM2 1815/4885PAOX 3482/4885NFKB1 172/4885 |
| US-20140256638-A1 | PEPTOID NEUTRALIZING AGENTS | SERPINC1, ANTXR2, VIP | CHRM2 4706/4885PAOX 3968/4885NFKB1 1536/4885 |
| US-20140274916-A1 | CYCLIC PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NGLY1, FPR1, REV1 | CHRM2 2495/4885PAOX 438/4885NFKB1 639/4885 |
| US-20140256639-A1 | PEPTOID NEUTRALIZING AGENTS | SERPINC1, ANTXR2, VIP | CHRM2 4706/4885PAOX 3968/4885NFKB1 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.