Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10044461 | 0.93 | CHRM2 (0.56) | CHRM2PAOXCYP1A2LMNATHRB | |
| SCHEMBL13573476 | 0.91 | CHRM2 (0.60) | CHRM2PAOXLMNATHRBBLM | |
| SCHEMBL10044468 | 0.91 | CHRM2 (0.60) | CHRM2PAOXLMNATHRBBLM | |
| SCHEMBL8087943 | 0.86 | — | — | |
| SCHEMBL3384214 | 0.82 | CHRM2 (0.46) | CHRM2CYP1A2LMNATHRBBLM | |
| SCHEMBL4285941 | 0.80 | CHRM2 (0.56) | CHRM2PAOXCYP1A2LMNATHRB | |
| SCHEMBL27497237 | 0.79 | CHRM2 (0.40) | CHRM2PAOXTDP1 | |
| SCHEMBL7082287 | 0.79 | KDM4C (0.43) | ALDH1A1 | |
| SCHEMBL14216628 | 0.79 | PAOX (0.34) | PAOX | |
| SCHEMBL16299313 | 0.78 | CHRM2 (0.44) | CHRM2PAOXLMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160219880-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NEW YORK UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| US-9364449-B2 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NEW YORK UNIVERSITY (US) | 2016-06-14 | — | — | US | disclosed |
| US-9364449-B2 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NEW YORK UNIVERSITY (US) | 2016-06-14 | — | — | US | disclosed |
| US-9315548-B2 | Peptoid oligomers, pharmaceutical compositions and methods of using the same | NEW YORK UNIVERSITY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150011465-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NEW YORK UNIVERSITY | 2015-01-08 | — | — | US | disclosed |
| US-20140274916-A1 | CYCLIC PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NATIONAL SCIENCE FOUNDATION | 2014-09-18 | — | — | US | disclosed |
| US-20140256639-A1 | PEPTOID NEUTRALIZING AGENTS | UNIV CALIFORNIA (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256638-A1 | PEPTOID NEUTRALIZING AGENTS | UNIV CALIFORNIA (US) | 2014-09-11 | — | — | US | disclosed |
| US-8828413-B2 | Peptoid oligomers, pharmaceutical compositions and methods of using the same | NEW YORK UNIVERSITY (US) | 2014-09-09 | — | — | US | disclosed |
| US-20120015883-A1 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-01-19 | — | — | US | disclosed |
| US-20120015883-A1 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-01-19 | — | — | US | disclosed |
| WO-2011156003-A2 | PEPTOID AND SYNTHETIC OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011465-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NOD2, VIP, NOD1 | CHRM2 4400/4885PAOX 103/4885CYP1A2 3687/4885 |
| US-20160219880-A1 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NOD2, VIP, NOD1 | CHRM2 4400/4885PAOX 103/4885CYP1A2 3687/4885 |
| US-20120015883-A1 | Peptoid and synthetic oligomers, pharmaceutical compositions and methods of using same | APP, IAPP, PSEN1 | CHRM2 2174/4885PAOX 395/4885CYP1A2 4120/4885 |
| US-20140256638-A1 | PEPTOID NEUTRALIZING AGENTS | SERPINC1, ANTXR2, VIP | CHRM2 4706/4885PAOX 3968/4885CYP1A2 4875/4885 |
| US-20140274916-A1 | CYCLIC PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | NGLY1, FPR1, REV1 | CHRM2 2495/4885PAOX 438/4885CYP1A2 3162/4885 |
| US-20140256639-A1 | PEPTOID NEUTRALIZING AGENTS | SERPINC1, ANTXR2, VIP | CHRM2 4706/4885PAOX 3968/4885CYP1A2 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.