SCHEMBL10050995

SCHEMBL10050995

O=C(O)C1COB(c2ccccc2)O1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 2/20 0.33
CASP6 P55212 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18210978 0.77
SCHEMBL18538227 0.72 LPL (0.32)
SCHEMBL11884641 0.71 PTGS2 (0.33)
SCHEMBL11882825 0.71 TSHR (0.33)
SCHEMBL12525632 0.71 SUCNR1 (0.35) POLBCASP6
SCHEMBL2680291 0.70 TSHR (0.48) POLB
SCHEMBL7458763 0.70 TSHR (0.48) POLB
SCHEMBL2680294 0.70 TSHR (0.48) POLB
SCHEMBL19681355 0.68 TDP1 (0.31)
SCHEMBL18538228 0.68 MAOA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
US-11001835-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2021-05-11 US disclosed
EP-3299463-B1 ENZYMATIC ENCODING NUEVOLUTION AS (DK) 2020-10-21 EP disclosed
US-20200216836-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2020-07-09 US disclosed
US-10669538-B2 Templated molecules and methods for using such molecules NUEVOLUTION A/S (DK) 2020-06-02 US disclosed
US-20190330618-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION AS (DK) 2019-10-31 US disclosed
US-10287576-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2019-05-14 US disclosed
US-20190136227-A1 METHOD FOR THE SYNTHESIS OF A BIFUNCTIONAL COMPLEX NUEVOLUTION AS (DK) 2019-05-09 US disclosed
US-9885035-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2018-02-06 US disclosed
US-8932992-B2 Templated molecules and methods for using such molecules NUEVOLUTION A/S (DK) 2015-01-13 US disclosed
US-20150011434-A1 METHOD FOR THE SYNTHESIS OF A BIFUNCTIONAL COMPLEX NUEVOLUTION A/S (DK) 2015-01-08 US disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
US-20130040823-A1 METHOD FOR THE SYNTHESIS OF A BIFUNCTIONAL COMPLEX NUEVOLUTION A/S (DK) 2013-02-14 US disclosed
US-8206901-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2012-06-26 US disclosed
US-8206901-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2012-06-26 US disclosed
US-7727713-B2 Templated molecules and methods for using such molecules NUEVOLUTION A/S (DK) 2010-06-01 US disclosed
US-20100016177-A1 TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES NUEVOLUTION A/S (DK) 2010-01-21 US disclosed
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2009-10-22 US disclosed
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES RNGTT, DUT, EMG1 SMN1; SMN2 3626/4885POLB 25/4885CASP6 4672/4885
US-20100016177-A1 TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES INTS6, ABL1, INMT SMN1; SMN2 3576/4885POLB 109/4885CASP6 2656/4885
US-10669538-B2 Templated molecules and methods for using such molecules ABL1, DHFR, TYMS SMN1; SMN2 3782/4885POLB 106/4885CASP6 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.