SCHEMBL10051721

SCHEMBL10051721

CCCOCC(COCCC)(COCCC)COCCC

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.38
THRB P10828 1/20 0.34
CES1 P23141 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12240798 0.94 THRB (0.36) HSD17B10THRBCES1
SCHEMBL16473877 0.91 THRB (0.35) HSD17B10THRBCES1
SCHEMBL14616902 0.91 HSD17B10 (0.33) HSD17B10THRBCES1
SCHEMBL14616850 0.91 HSD17B10 (0.33) HSD17B10THRBCES1
SCHEMBL14616849 0.91 HSD17B10 (0.33) HSD17B10THRBCES1
SCHEMBL25457062 0.89 HSD17B10 (0.32) HSD17B10THRB
SCHEMBL12667484 0.88 THRB (0.45) HSD17B10THRBCES1
SCHEMBL15087186 0.88 THRB (0.41) HSD17B10THRBCES1
SCHEMBL9881090 0.88 THRB (0.45) HSD17B10THRBCES1
SCHEMBL20089590 0.87 THRB (0.38) HSD17B10THRBCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10784051-B2 Dye-sensitized photoelectric conversion element NSK LTD. (JP) 2020-09-22 US disclosed
US-20200211787-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT NSK LTD. (JP) 2020-07-02 US disclosed
EP-2621455-B1 POLYMERIZABLE DENTAL MATERIAL COMPRISING A REACTIVE PASTE FORMER, HARDENED DENTAL MATERIAL AND USE THEREOF KETTENBACH GMBH & CO KG (DE) 2019-06-26 EP disclosed
US-20170114245-A1 DISPERSION COMPOSITION, CURABLE COMPOSITION USING THE SAME, TRANSPARENT FILM, MICROLENS AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2017-04-27 US disclosed
US-9517278-B2 Compound and photoacoustic imaging contrast medium containing the compound CANON KABUSHIKI KAISHA (JP) 2016-12-13 US disclosed
US-9114079-B2 Polymerizable dental material comprising reactive paste formers, hardened dental material and use thereof KETTENBACH GMBH & CO. KG (DE) 2015-08-25 US disclosed
US-9114079-B2 Polymerizable dental material comprising reactive paste formers, hardened dental material and use thereof KETTENBACH GMBH & CO. KG (DE) 2015-08-25 US disclosed
US-20150165071-A1 COMPOUND AND PHOTOACOUSTIC IMAGING CONTRAST MEDIUM CONTAINING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2015-06-18 US disclosed
US-20130225699-A1 Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof KETTENBACH GMBH & CO. KG (DE) 2013-08-29 US disclosed
US-20130225699-A1 Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof KETTENBACH GMBH & CO. KG (DE) 2013-08-29 US disclosed
US-20130018010-A1 POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS ENZON PHARMACEUTICALS, INC. (US) 2013-01-17 US disclosed
WO-2012052249-A2 POLYMERIZABLE DENTAL MATERIAL COMPRISING REACTIVE PASTE FORMERS, HARDENED DENTAL MATERIAL AND USE THEREOF KETTENBACH GMBH & CO. KG (DE) 2012-04-26 WO disclosed
US-20070025956-A1 Polymer-based compositions and conjugates of non-steroidal anti-inflammatory drugs NEKTAR THERAPEUTICS AL, CORPORATION (US) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225699-A1 Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof ME1, ME2, ME3 HSD17B10 1139/4885THRB 2431/4885CES1 3263/4885
US-20070025956-A1 Polymer-based compositions and conjugates of non-steroidal anti-inflammatory drugs HPGDS, PTGES, PTGS1 HSD17B10 681/4885THRB 4754/4885CES1 316/4885
US-20130018010-A1 POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS VEGFA, MKI67, PCNA HSD17B10 4271/4885THRB 4646/4885CES1 3928/4885
US-20150165071-A1 COMPOUND AND PHOTOACOUSTIC IMAGING CONTRAST MEDIUM CONTAINING THE COMPOUND CLTB, PAM, CLTA HSD17B10 3323/4885THRB 3460/4885CES1 3750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.