Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GLA | P06280 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966873 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1GLAGAANPC1 | |
| SCHEMBL23533799 | 0.92 | PARP1 (0.47) | KDM4EALDH1A1GLAGAANPC1 | |
| SCHEMBL31195892 | 0.76 | TLR8 (0.38) | ALDH1A1GAANPC1HSD17B10PARP1 | |
| SCHEMBL1650122 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1GLAGAANPC1 | |
| SCHEMBL21656372 | 0.75 | RAB9A (0.40) | KDM4EALDH1A1GLAGAANPC1 | |
| SCHEMBL14929656 | 0.75 | TLR7 (0.49) | KDM4EALDH1A1GLAGAANPC1 | |
| SCHEMBL18721046 | 0.73 | DRD1 (0.40) | KDM4EALDH1A1GAANPC1HSD17B10 | |
| SCHEMBL21622755 | 0.73 | GABRA1 (0.64) | KDM4EALDH1A1GLAGAANPC1 | |
| SCHEMBL21622880 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1GLAGAANPC1 | |
| SCHEMBL13852951 | 0.73 | CYP2A6 (0.44) | ALDH1A1NPC1HSD17B10RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170324046-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | HEESUNG MATERIAL LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-9382253-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2016-07-05 | — | — | US | disclosed |
| US-9382253-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2016-07-05 | — | — | US | disclosed |
| US-9382253-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2016-07-05 | — | — | US | disclosed |
| US-20130112921-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130112921-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130112921-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012007087-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130112921-A1 | METAL COMPLEXES | MCOLN2, MCOLN1, NCLN | KDM4E 3819/4885ALDH1A1 3236/4885GLA 3458/4885 |
| US-20170324046-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | CRY1, CRY2, PER2 | KDM4E 1752/4885ALDH1A1 953/4885GLA 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.