Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | ANPEP | P15144 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411355 | 0.72 | KEAP1 (0.46) | KEAP1NFE2L2 | |
| SCHEMBL14815575 | 0.72 | ANPEP (0.49) | PLAUMTNR1AMTNR1BANPEPGRIN2B | |
| SCHEMBL10062424 | 0.71 | TSHR (0.43) | MTNR1AMTNR1BCA1CA2CYP1A2 | |
| SCHEMBL19393068 | 0.71 | PLAU (0.50) | PLAUMTNR1AMTNR1BANPEPCA1 | |
| SCHEMBL5028027 | 0.71 | PLAU (0.50) | PLAUMTNR1AMTNR1BANPEPCA1 | |
| Oxalic Acid SCHEMBL7860177 | 0.70 | PLAU (0.78) | PLAUMTNR1AMTNR1BANPEP | |
| SCHEMBL9567951 | 0.70 | MTNR1A (0.42) | PLAUMTNR1AMTNR1BANPEPCA1 | |
| SCHEMBL9568069 | 0.70 | MTNR1A (0.44) | PLAUMTNR1AMTNR1BANPEPCA1 | |
| SCHEMBL16595708 | 0.69 | PNMT (0.39) | MTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL367535 | 0.69 | FAAH (0.53) | PLAUMTNR1AMTNR1BANPEPAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173710-B2 | Bicyclic sphingosine 1-phosphate analogs | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110195936-A1 | BICYCLIC SPHINGOSINE 1-PHOSPHATE ANALOGS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195936-A1 | BICYCLIC SPHINGOSINE 1-PHOSPHATE ANALOGS | S1PR1, S1PR4, S1PR3 | PLAU 3997/4885MTNR1A 1520/4885MTNR1B 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.