SCHEMBL10068075

SCHEMBL10068075

CCOC(=O)[C@@](C)(CCCC(=O)O)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.41
CYP4A11 Q02928 2/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.40
MMP8 P22894 2/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AKR1B1 P15121 1/20 0.36
GPR84 Q9NQS5 6/20 0.35
PPARG P37231 6/20 0.35
PPARD Q03181 6/20 0.35
PPARA Q07869 6/20 0.35
HDAC11 Q96DB2 5/20 0.35
TSHR P16473 4/20 0.35
ALDH1A1 P00352 2/20 0.35
TLR2 O60603 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9263994 0.86 CYP1A2 (0.47) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL13084351 0.84 MEN1 (0.47) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL25697482 0.83 TSHR (0.44) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL41296 0.82 MEN1 (0.46) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL10001105 0.82 MEN1 (0.54) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL10001106 0.81 CYP4F2 (0.64) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL1406736 0.81 THRB (0.42) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL4100780 0.80 CYP4F2 (0.62) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL304464 0.80 CYP4F2 (0.46) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL16976302 0.80 MMP8 (0.44) CYP4F2CYP4A11THRBPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9110069-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2015-08-18 US disclosed
US-20140086844-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC (US) 2014-03-27 US disclosed
US-8642014-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2014-02-04 US disclosed
US-8552027-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2013-10-08 US disclosed
US-20120035346-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2012-02-09 US disclosed
US-20100266507-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2010-10-21 US disclosed
US-7411068-B2 Luminescent compounds SETA BIOMEDICALS, LLC 2008-08-12 US disclosed
US-20070281363-A1 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence Terpetschnig, Ewald (US) 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100266507-A1 LUMINESCENT COMPOUNDS SQLE, COASY, ZKSCAN2 CYP4F2 3003/4885CYP4A11 4459/4885THRB 3434/4885
US-20140086844-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS CYP4F2 3491/4885CYP4A11 4297/4885THRB 4334/4885
US-20120035346-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS CYP4F2 3470/4885CYP4A11 4250/4885THRB 4505/4885
US-20070281363-A1 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence SPR, SRRT, SQLE CYP4F2 3362/4885CYP4A11 3461/4885THRB 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.