SCHEMBL316754

SCHEMBL316754

CC(C)(C)OC(=O)[C@@H](N1C(=O)c2ccc(OCc3ccccc3)cc2C1=O)C(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
TOP1 P11387 1/20 0.45
LTA4H P09960 1/20 0.45
MAOB P27338 8/20 0.44
MAOA P21397 6/20 0.44
PPARG P37231 1/20 0.44
GRM5 P41594 2/20 0.43
PRKCA P17252 1/20 0.40
PRKCD Q05655 1/20 0.40
YAP1 P46937 1/20 0.40
SRD5A2 P31213 1/20 0.39
LMNA P02545 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL315870 0.89 POLB (0.50) POLBTOP1MAOBMAOAPPARG
SCHEMBL7377987 0.83 LTA4H (0.46) POLBTOP1LTA4HMAOBMAOA
SCHEMBL25667517 0.80 LMNA (0.43) POLBLMNA
SCHEMBL316315 0.79 MEN1 (0.43) POLBMAOBMAOA
SCHEMBL316509 0.78 L3MBTL1 (0.35) L3MBTL1
SCHEMBL10068087 0.73 L3MBTL1 (0.49) PPARGL3MBTL1
SCHEMBL26932025 0.73 ALDH1A1 (0.40) POLBLMNAL3MBTL1
SCHEMBL30683055 0.73 ALDH1A1 (0.40) POLBLMNAL3MBTL1
SCHEMBL27446439 0.72 POLB (0.51) POLBTOP1MAOBMAOAPPARG
SCHEMBL26874903 0.72 PPARA (0.49) POLBLTA4HMAOBPPARGPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045014-B1 POLYMER-SUPPORTED METAL COMPLEX CATALYST UNIV HOKKAIDO NAT UNIV CORP (JP) 2014-01-15 EP disclosed
US-8092720-B2 Polymer-supported metal complex catalyst NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2012-01-10 US disclosed
US-8092720-B2 Polymer-supported metal complex catalyst NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2012-01-10 US disclosed
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2009-09-10 US disclosed
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2009-09-10 US disclosed
EP-2045014-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST National University Corporation Hokkaido University (JP) 2009-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST PYM1, ARG1, SCO2 POLB 956/4885TOP1 1226/4885LTA4H 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.