SCHEMBL10037556

SCHEMBL10037556

C=Cc1ccc(COCCCOc2ccc3c(c2)C(=O)N([C@H](C(=O)O)C(C)(C)C)C3=O)cc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
KMT2A Q03164 3/20 0.34
POLB P06746 1/20 0.34
BCL2 P10415 3/20 0.34
BCL2L2 Q92843 3/20 0.34
BAD Q92934 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
RAB9A P51151 1/20 0.34
PPARA Q07869 3/20 0.33
CYP2D6 P10635 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ITGB3 P05106 1/20 0.32
ITGA2B P08514 1/20 0.32
PPARD Q03181 1/20 0.32
LNPEP Q9UIQ6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316517 0.97 L3MBTL1 (0.38) L3MBTL1KMT2APOLBBCL2BCL2L2
SCHEMBL316509 0.88 L3MBTL1 (0.35) L3MBTL1KMT2ABCL2BCL2L2BAD
SCHEMBL316521 0.81 L3MBTL1 (0.51) L3MBTL1KMT2APOLBBCL2BCL2L2
SCHEMBL10068087 0.80 L3MBTL1 (0.49) L3MBTL1KMT2AMEN1MAPTNPC1
SCHEMBL315870 0.78 POLB (0.50) L3MBTL1KMT2APOLBALDH1A1GAA
SCHEMBL316754 0.69 POLB (0.47) L3MBTL1POLB
SCHEMBL317136 0.68 MEN1 (0.53) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL2267205 0.67 TDP1 (0.46) L3MBTL1NPC1ALDH1A1RAB9ATDP1
SCHEMBL316695 0.66 ALDH1A1 (0.46) L3MBTL1MAPTALDH1A1TDP1
SCHEMBL21278424 0.64 CHRNB2 (0.42) L3MBTL1KMT2AMEN1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092720-B2 Polymer-supported metal complex catalyst NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2012-01-10 US disclosed
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST PYM1, ARG1, SCO2 L3MBTL1 2735/4885KMT2A 305/4885POLB 956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.