Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 6/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | CASP9 | P55211 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP5 | P51878 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674857 | 0.98 | CASP1 (0.50) | CASP1CASP3CASP9CASP7TASP1 | |
| SCHEMBL13194679 | 0.98 | CASP1 (0.50) | CASP1CASP3CASP9CASP7TASP1 | |
| SCHEMBL4100803 | 0.98 | CASP1 (0.50) | CASP1CASP3CASP9CASP7TASP1 | |
| SCHEMBL29310042 | 0.98 | CASP1 (0.50) | CASP1CASP3CASP9CASP7TASP1 | |
| SCHEMBL29802264 | 0.93 | TASP1 (0.51) | CASP1CASP3CASP9CASP7TASP1 | |
| SCHEMBL20257263 | 0.91 | TASP1 (0.53) | CASP1CASP3CASP9CASP7TASP1 | |
| SCHEMBL20257260 | 0.91 | TASP1 (0.53) | CASP1CASP3CASP9CASP7TASP1 | |
| SCHEMBL29664642 | 0.87 | CASP1 (0.47) | CASP1CASP3CASP9CASP7CASP4 | |
| SCHEMBL29946268 | 0.85 | TASP1 (0.51) | CASP1TASP1GNPATBACE1BACE2 | |
| SCHEMBL23133189 | 0.84 | CASP1 (0.49) | CASP1CASP3CASP9CASP7TASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | CASP1 2900/4885CASP3 3030/4885CASP9 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.