SCHEMBL1674857

SCHEMBL1674857

CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 5/20 0.50
CASP3 P42574 3/20 0.50
CASP9 P55211 3/20 0.50
CASP7 P55210 1/20 0.50
GNPAT O15228 1/20 0.43
TASP1 Q9H6P5 1/20 0.43
ENPEP Q07075 5/20 0.42
BACE1 P56817 4/20 0.41
BACE2 Q9Y5Z0 2/20 0.41
CASP4 P49662 1/20 0.41
CASP5 P51878 1/20 0.41
CASP6 P55212 1/20 0.41
CASP8 Q14790 1/20 0.41
CASP10 Q92851 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
BMP1 P13497 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13194679 1.00 CASP1 (0.50) CASP1CASP3CASP9CASP7GNPAT
SCHEMBL29310042 1.00 CASP1 (0.50) CASP1CASP3CASP9CASP7GNPAT
SCHEMBL4100803 1.00 CASP1 (0.50) CASP1CASP3CASP9CASP7GNPAT
SCHEMBL10068454 0.98 CASP1 (0.47) CASP1CASP3CASP9CASP7GNPAT
SCHEMBL29802264 0.93 TASP1 (0.51) CASP1CASP3CASP9CASP7TASP1
SCHEMBL20257260 0.91 TASP1 (0.53) CASP1CASP3CASP9CASP7TASP1
SCHEMBL20257263 0.91 TASP1 (0.53) CASP1CASP3CASP9CASP7TASP1
SCHEMBL29664642 0.87 CASP1 (0.47) CASP1CASP3CASP9CASP7ENPEP
SCHEMBL23133189 0.87 CASP1 (0.49) CASP1CASP3CASP9CASP7GNPAT
SCHEMBL23133187 0.87 CASP1 (0.49) CASP1CASP3CASP9CASP7GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119000835-A Preparation method of cylindrical magnetic bio-MOF modified electrode and application of cylindrical magnetic bio-MOF modified electrode in Caspase-3 detection 宁波大学 2024-11-22 CN claimed
US-20240287457-A1 COMPOSITIONS AND CELL CULTURE MEDIA FOR INCREASING NEUTROPHIL LIFESPAN THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-08-29 US claimed
US-20240268372-A1 Methods and Compositions for Extending Organ and Tissue Preservation MASSACHUSETTS GEN HOSPITAL (US) 2024-08-15 US claimed
CN-118044505-A Fresh tissue preservation solution and preparation method and application thereof 北京百奥智汇科技有限公司 2024-05-17 CN claimed
CN-118048314-A Preparation method of additive factors for enhancing hybridoma fusion 苏州博特龙免疫技术有限公司 2024-05-17 CN claimed
US-20240115649-A1 CASPASE INHIBITION TO ENHANCE REGENERATION AND REPAIR AFTER SKIN OR GUT INJURY AND TO TREAT BACTERIAL OR VIRAL INFECTIONS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-04-11 US claimed
US-11879893-B2 Rapid detection test for SARS-CoV-2 NLC PHARMA LTD (IL) 2024-01-23 US claimed
CN-117004565-A Culture combination and culture method for obtaining T cells from cryopreserved PBMC 上海细胞治疗集团有限公司 2023-11-07 CN claimed
CN-114891726-B Human totipotent stem cell induction culture medium and application thereof 中山大学 2023-04-28 CN claimed
US-20230090502-A1 RAPID DETECTION TEST FOR SARS-COV-2 NLC PHARMA LTD (IL) 2023-03-23 US claimed
WO-2022266046-A1 COMPOSITIONS AND CELL CULTURE MEDIA FOR INCREASING NEUTROPHIL LIFESPAN THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2022-12-22 WO claimed
EP-4097244-A2 RAPID DETECTION TEST FOR SARS-COV-2 NLC Pharma Ltd (IL) 2022-12-07 EP claimed
CN-115386538-A Method for separating, extracting and culturing endometrial stem cells from menstrual blood and special culture medium 上海长一干细胞研究中心有限公司 2022-11-25 CN claimed
CN-115381445-A Menstrual blood collector for human menstrual blood, preservation solution and matched preservation and transportation device 上海长一干细胞研究中心有限公司 2022-11-25 CN claimed
WO-2022241417-A1 METHODS AND COMPOSITIONS FOR EXTENDING ORGAN AND TISSUE PRESERVATION THE GENERAL HOSPITAL CORPORATION (US) 2022-11-17 WO claimed
CN-115335532-A SARS-COV-2 quick detection test NLC制药有限公司 2022-11-11 CN claimed
CN-114891726-A Human totipotent-like stem cell induction culture medium and application thereof 中山大学 2022-08-12 CN claimed
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-21 US disclosed
WO-1999041398-A1 VECTORS, CELLS AND METHODS FOR THE PRODUCTION OF DELETERIOUS VIRAL EUKARYOTIC GENE TRANSFER VECTORS GENVEC, INC. (US) 1999-08-19 WO disclosed
WO-1999009208-A1 METHOD AND REAGENT FOR MONITORING APOPTOSIS AND DISTINGUISHING APOPTOSIS FROM NECROSIS COULTER INTERNATIONAL CORP. (US) 1999-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137691-A1 WB3 FOR ANESTHESIA AND TREATING PAIN WNT3, TRPV3, ADRB3 CASP1 628/4885CASP3 39/4885CASP9 845/4885
US-20240287457-A1 COMPOSITIONS AND CELL CULTURE MEDIA FOR INCREASING NEUTROPHIL LIFESPAN MMP8, NCF1, ELANE CASP1 106/4885CASP3 595/4885CASP9 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.