Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069591 | 0.92 | ESR1 (0.35) | LMNAPDE10AESR1KDM5B | |
| SCHEMBL10069619 | 0.90 | KDM5B (0.34) | MAPTKDM5BL3MBTL1 | |
| SCHEMBL10069601 | 0.89 | ALDH1A1 (0.36) | GRM5L3MBTL1 | |
| SCHEMBL10069611 | 0.89 | L3MBTL1 (0.36) | SMN1; SMN2GRM5L3MBTL1 | |
| SCHEMBL10069629 | 0.86 | RGS4 (0.35) | MAPTLMNASMN1; SMN2POLBGRM5 | |
| SCHEMBL10069631 | 0.86 | RGS4 (0.34) | ANO1SMN1; SMN2KDM5BGRM5 | |
| SCHEMBL10069598 | 0.85 | TP53 (0.33) | MAPTGRM5 | |
| SCHEMBL10069596 | 0.85 | MAPT (0.36) | MAPTLMNASMN1; SMN2POLBHTT | |
| SCHEMBL10069599 | 0.84 | PTGS2 (0.34) | MAPTLMNASMN1; SMN2POLBSTAT3 | |
| SCHEMBL10069624 | 0.83 | GHSR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |