Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069590 | 0.93 | ALDH1A1 (0.39) | ALDH1A1MAPK1ERCC5FEN1ELANE | |
| SCHEMBL10069601 | 0.90 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL10069594 | 0.90 | MAPT (0.38) | ALDH1A1KDM4EMAPTERCC5FEN1 | |
| SCHEMBL10069595 | 0.90 | ALDH1A1 (0.38) | ALDH1A1MAPK1ERCC5FEN1ERCC1 | |
| SCHEMBL10069631 | 0.89 | RGS4 (0.34) | ALDH1A1KMT2AKDM4EARSMN1; SMN2 | |
| SCHEMBL10069606 | 0.89 | ALDH1A1 (0.37) | ALDH1A1KMT2AMAPTMAPK1ERCC5 | |
| SCHEMBL10069592 | 0.88 | MEN1 (0.40) | ALDH1A1MEN1KMT2AKDM4EAR | |
| SCHEMBL10069591 | 0.87 | ESR1 (0.35) | ALDH1A1MEN1KMT2AMAPK1ERCC5 | |
| SCHEMBL10069611 | 0.86 | L3MBTL1 (0.36) | ALDH1A1KDM4EARSMN1; SMN2L3MBTL1 | |
| SCHEMBL10069619 | 0.84 | KDM5B (0.34) | MAPTARL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |