Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.59 |
| ▸ | MMP13 | P45452 | 3/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12548449 | 0.79 | PLA2G4A (0.59) | MMP1MMP13MMP2MMP9HDAC1 | |
| SCHEMBL5725599 | 0.77 | MMP2 (0.53) | MMP1MMP13MMP2MMP9HDAC1 | |
| SCHEMBL11959465 | 0.76 | MMP1 (0.54) | MMP1MMP13MMP2MMP9HDAC1 | |
| SCHEMBL26319518 | 0.76 | ALDH1A1 (0.73) | HDAC1HDAC8HDAC6PTPN1ALDH1A1 | |
| SCHEMBL10277057 | 0.76 | MMP1 (0.49) | MMP1MMP13MMP2MMP9HDAC1 | |
| SCHEMBL3568125 | 0.75 | MAPT (0.56) | MMP1MMP13MMP2MMP9HPGDS | |
| SCHEMBL12850172 | 0.75 | MMP13 (0.67) | MMP1MMP13MMP2MMP9HDAC1 | |
| SCHEMBL10076594 | 0.75 | MMP13 (1.00) | MMP1MMP13MMP2MMP9 | |
| SCHEMBL1246008 | 0.74 | PLA2G4A (0.55) | MMP1MMP13MMP2MMP9ALDH1A1 | |
| SCHEMBL1977126 | 0.74 | HDAC1 (0.72) | MMP1MMP13MMP2MMP9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651413-B1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT (HU) | 2017-11-22 | — | — | EP | disclosed |
| US-9487462-B2 | Inhibitors of matrix metalloproteinases | PHARMAHUNGARY 2000 KFT. (HU) | 2016-11-08 | — | — | US | disclosed |
| US-9487462-B2 | Inhibitors of matrix metalloproteinases | PHARMAHUNGARY 2000 KFT. (HU) | 2016-11-08 | — | — | US | disclosed |
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TARGETEX KFT. (HU) | 2013-11-14 | — | — | US | disclosed |
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TARGETEX KFT. (HU) | 2013-11-14 | — | — | US | disclosed |
| WO-2012080762-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT. (HU) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TIMP3, MMP3, MMP13 | MMP1 4/4885MMP13 3/4885MMP2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.