Sugi Predict

Sugi Predict / Compounds / SCHEMBL10078863

SCHEMBL10078863

SCHEMBL10078863

Cc1cc(C)cc(-c2ccc3ccc(-c4ccccc4)cc3n2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IGF1R P08069 1/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ GAA P10253 1/20 0.45
▸ NPC1 O15118 3/20 0.45
▸ RAB9A P51151 3/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ KDM4E B2RXH2 4/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ GMNN O75496 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ THPO P40225 1/20 0.44
▸ BLM P54132 1/20 0.44
▸ PMP22 Q01453 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28354939 0.91 DHODH (0.44) IGF1RL3MBTL1GAANPC1RAB9A
SCHEMBL19996748 0.89 BACE1 (0.54) L3MBTL1GAANPC1RAB9AMEN1
SCHEMBL17453342 0.85 MAPK14 (0.40) NPC1RAB9AMEN1KMT2A
SCHEMBL10039876 0.84 RAB9A (0.55) IGF1RL3MBTL1NPC1RAB9AMEN1
SCHEMBL17453337 0.83 MEN1 (0.38) IGF1RL3MBTL1NPC1RAB9AMEN1
SCHEMBL19996754 0.83 IGF1R (0.44) IGF1RL3MBTL1GAANPC1RAB9A
SCHEMBL29638020 0.82 NPC1 (0.59) L3MBTL1GAANPC1RAB9AMEN1
SCHEMBL10079213 0.82 NPC1 (0.59) L3MBTL1GAANPC1RAB9AMEN1
SCHEMBL26550788 0.81 NPC1 (0.58) L3MBTL1GAANPC1RAB9AMEN1
SCHEMBL13989404 0.80 CYP1A2 (0.55) L3MBTL1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
CN-110790793-A Organic electroluminescent material and device 环球展览公司 2020-02-14 — — CN disclosed
CN-105295895-B organic electroluminescent material and device 环球展览公司 2019-11-05 — — CN disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
US-10230060-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-03-12 — — US disclosed
EP-3327100-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2018-05-30 — — EP disclosed
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-24 — — US disclosed
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-24 — — US disclosed
US-9929357-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-27 — — US disclosed
US-9142786-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 — — US disclosed
US-20130248832-A1 Phosphorescent Materials UNIVERSAL DISPLAY CORPORATION 2013-09-26 — — US disclosed
US-20130248832-A1 Phosphorescent Materials UNIVERSAL DISPLAY CORPORATION 2013-09-26 — — US disclosed
US-8431243-B2 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2013-04-30 — — US disclosed
US-8431243-B2 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2013-04-30 — — US disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 — — EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 — — EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 IGF1R 2300/4885L3MBTL1 2975/4885GAA 3377/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 IGF1R 40/4885L3MBTL1 37/4885GAA 4367/4885
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, ICMT IGF1R 3458/4885L3MBTL1 978/4885GAA 2517/4885
US-10230060-B2 Organic electroluminescent materials and devices RUVBL2, OR10J3, EML4 IGF1R 51/4885L3MBTL1 14/4885GAA 4354/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 IGF1R 21/4885L3MBTL1 131/4885GAA 4387/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN IGF1R 3644/4885L3MBTL1 1670/4885GAA 2412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.