SCHEMBL10082969

SCHEMBL10082969

Cn1c2ccc1cc1nc(cc3ccc(cc4nc(c2)C=C4)[nH]3)C=C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.33
▸ STAT1 P42224 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14812116 0.83 STAT3 (0.34) STAT3STAT1
SCHEMBL29430977 0.82 STAT3 (0.42) STAT3STAT1
SCHEMBL6744970 0.82 STAT3 (0.42) STAT3STAT1
SCHEMBL30821407 0.82 STAT3 (0.42) STAT3STAT1
SCHEMBL9430673 0.82 STAT3 (0.42) STAT3STAT1
SCHEMBL15809 0.82 STAT3 (0.42) STAT3STAT1
SCHEMBL6517023 0.82 STAT3 (0.42) STAT3STAT1
SCHEMBL9405017 0.81 STAT3 (0.33) STAT3STAT1
Bromomethane SCHEMBL909355 0.80 STAT3 (0.39) STAT3STAT1
Chloromethane SCHEMBL5164781 0.80 STAT3 (0.39) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117042600-A Anti-influenza a animals with edited ANP32 gene 猪改良英国有限公司 2023-11-10 — — CN disclosed
US-9530571-B2 Compound and support material supporting this novel compound ADEKA CORPORATION (JP) 2016-12-27 — — US disclosed
US-20140261647-A1 NOVEL COMPOUND AND SUPPORT MATERIAL SUPPORTING THIS NOVEL COMPOUND ADEKA CORPORATION (JP) 2014-09-18 — — US disclosed
US-20140155609-A9 QUINOLINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME DONG-A ST CO., LTD. (KR) 2014-06-05 — — US disclosed
US-20130296571-A1 QUINOLINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME DONG-A ST CO., LTD. (KR) 2013-11-07 — — US disclosed
EP-1492799-B1 COMPOUNDS USEFUL AS PHOTODYNAMIC THERAPEUTIC AGENTS HAE THERAPEUTICS LTD (IE) 2013-09-11 — — EP disclosed
US-20120077959-A1 Asymmetric Cobalt-Catalyzed Cyclopropanation With Succinimidyl Diazoacetate NATIONAL SCIENCE FOUNDATION 2012-03-29 — — US disclosed
US-8110699-B2 Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates UNIVERSITY OF SOUTH FLORIDA (US) 2012-02-07 — — US disclosed
US-20100081838-A1 Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates UNIVERSITY OF SOUTH FLORIDA (US) 2010-04-01 — — US disclosed
US-20100076239-A1 ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS UNIVERSITY OF SOUTH FLORIDA (US) 2010-03-25 — — US disclosed
EP-1900429-B1 Light energy conversion material TOYOTA CHUO KENKYUSHO KK (JP) 2009-05-27 — — EP disclosed
US-4386087-A COPPER DERIVATIVE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 1983-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140155609-A9 QUINOLINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME SLC10A2, VIP, SI STAT3 3003/4885STAT1 4316/4885
US-20130296571-A1 QUINOLINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME SLC10A2, VIP, SI STAT3 3003/4885STAT1 4316/4885
US-20100076239-A1 ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS DUOX2, DUOX1, PPOX STAT3 4433/4885STAT1 4250/4885
US-20100081838-A1 Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates PPOX, IDH3A, HMOX2 STAT3 3538/4885STAT1 2043/4885
US-20120077959-A1 Asymmetric Cobalt-Catalyzed Cyclopropanation With Succinimidyl Diazoacetate SI, STOM, SUCLA2 STAT3 2670/4885STAT1 2801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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