Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592771 | 0.85 | JAK2 (0.44) | ESR1ESR2JAK2ROCK2PRKCQ | |
| SCHEMBL11479931 | 0.79 | GRM1 (0.46) | ESR1ESR2ALDH1A1CYP3A4CA12 | |
| SCHEMBL10183753 | 0.79 | HDAC4 (0.42) | ESR1ESR2ALDH1A1HSD17B10ACHE | |
| SCHEMBL5057717 | 0.79 | GABRA1 (0.48) | ESR1ESR2ALDH1A1CYP3A4LMNA | |
| SCHEMBL9080223 | 0.78 | PRKCQ (0.44) | ESR1ESR2ALDH1A1CYP3A4CA12 | |
| SCHEMBL2442297 | 0.78 | ACHE (0.44) | ALDH1A1CYP3A4LMNAACHEJAK2 | |
| Resorcinol SCHEMBL28005416 | 0.77 | ALDH1A1 (0.55) | ESR1ESR2ALDH1A1CYP3A4CA12 | |
| SCHEMBL13531100 | 0.77 | ALDH1A1 (0.48) | ESR1ESR2ALDH1A1CYP3A4CA12 | |
| SCHEMBL2957052 | 0.76 | ESR1 (0.54) | ESR1ESR2ALDH1A1CYP3A4CA12 | |
| SCHEMBL1492513 | 0.76 | ESR1 (0.68) | ESR1ESR2ALDH1A1CYP3A4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1252017-C | 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage | UNIV WUHAN (CN) | 2006-04-19 | — | — | CN | claimed |
| CN-1252018-C | 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage | UNIV WUHAN (CN) | 2006-04-19 | — | — | CN | claimed |
| CN-1252024-C | 3-[2-benzyloxy-4-(1,1-dimethyl octyl) phenyl] cycllhexanone, synthetic method and usage | UNIV WUHAN (CN) | 2006-04-19 | — | — | CN | claimed |
| CN-1562929-A | 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage | UNIV WUHAN (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1562928-A | 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage | UNIV WUHAN (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1562935-A | 3-[2-benzyloxy-4-(1,1-dimethyl octyl) phenyl] cycllhexanone, synthetic method and usage | UNIV WUHAN (CN) | 2005-01-12 | — | — | CN | claimed |
| EP-2785695-B1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-06-17 | — | — | EP | disclosed |
| EP-3517109-A1 | COMPOUNDS AND METHOD FOR REDUCING URIC ACID | Wellstat Therapeutics Corporation (US) | 2019-07-31 | — | — | EP | disclosed |
| EP-2268141-B1 | COMPOUND AND METHOD FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORP (US) | 2019-05-08 | — | — | EP | disclosed |
| US-9115072-B2 | Compounds and method for reducing uric acid | WELLSTAT THERAPEUTICS CORPORATION (US) | 2015-08-25 | — | — | US | disclosed |
| CN-101969773-B | compounds and methods for reducing uric acid | WELLSTAT THERAPEUTICS CORP. (US) | 2015-08-19 | — | — | CN | disclosed |
| CN-102976928-B | Compounds for reducing uric acid | WELLSTAT THERAPEUTICS CORP | 2014-09-17 | — | — | CN | disclosed |
| US-20130259850-A1 | COMPOUNDS AND METHOD FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-10-03 | — | — | US | disclosed |
| CN-1252018-C | 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage | UNIV WUHAN (CN) | 2006-04-19 | — | — | CN | disclosed |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | CARTER JEFFERY (US) | 2005-07-07 | — | — | US | disclosed |
| CN-1562935-A | 3-[2-benzyloxy-4-(1,1-dimethyl octyl) phenyl] cycllhexanone, synthetic method and usage | UNIV WUHAN (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1562929-A | 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage | UNIV WUHAN (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1562928-A | 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage | UNIV WUHAN (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1562928-A | 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage | UNIV WUHAN (CN) | 2005-01-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148777-A1 | Benzopyran compounds useful for treating inflammatory conditions | PTGES2, PTGER2, PTGS2 | ESR1 698/4885ESR2 80/4885ALDH1A1 560/4885 |
| US-20130259850-A1 | COMPOUNDS AND METHOD FOR REDUCING URIC ACID | RCC2, HAX1, SLC10A6 | ESR1 3314/4885ESR2 1742/4885ALDH1A1 3768/4885 |
| US-20050148627-A1 | Benzopyran compounds for use in the treatment and prevention of inflammation related conditions | PTGES2, PTGER2, PTGES | ESR1 266/4885ESR2 42/4885ALDH1A1 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.