SCHEMBL508579

SCHEMBL508579

O=C(CCCCC(=O)OCC(Cl)(Cl)Cl)OCC(Cl)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.41
PAM P19021 2/20 0.38
CYP1A2 P05177 1/20 0.37
TSHR P16473 3/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
DNM1 Q05193 1/20 0.34
CYP3A4 P08684 1/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.32
RECQL P46063 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCE Q02156 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10105403 0.95 TSHR (0.40) DGKAPAMCYP1A2TSHRMAPT
SCHEMBL26983152 0.91 LMNA (0.46) PAMTSHRALDH1A1LMNATDP1
SCHEMBL3165640 0.91 DGKA (0.36) DGKAPAMCYP1A2TSHRMAPT
SCHEMBL7439614 0.90 ADRA2A (0.37) DGKACYP1A2TSHRMAPTALDH1A1
SCHEMBL15561379 0.89 GPR84 (0.41) DGKAPAMTSHRMAPTALDH1A1
SCHEMBL16487386 0.89 DGKA (0.39) DGKAPAMCYP1A2TSHRMAPT
SCHEMBL3166498 0.89 CYP1A2 (0.48) DGKAPAMCYP1A2TSHRMAPT
SCHEMBL4908232 0.89 DGKA (0.59) DGKAPAMTSHRMAPTALDH1A1
SCHEMBL15561347 0.89 GPR84 (0.41) DGKAPAMTSHRMAPTALDH1A1
SCHEMBL8894297 0.89 DGKA (0.33) DGKAPAMCYP1A2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5270421-A Sucrose-organic acid units UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1993-12-14 US claimed
CN-118084915-A Clean synthesis method of pyromellitic acid diimide 河北科技大学 2024-05-28 CN disclosed
US-9297252-B2 Use of long chain amines and difunctional compounds as tracers BAKER HUGHES INCORPORATED (US) 2016-03-29 US disclosed
US-9297252-B2 Use of long chain amines and difunctional compounds as tracers BAKER HUGHES INCORPORATED (US) 2016-03-29 US disclosed
US-20150377010-A1 USE OF LONG CHAIN AMINES AND DIFUNCTIONAL COMPOUNDS AS TRACERS BAKER HUGHES INCORPORATED (US) 2015-12-31 US disclosed
US-20150377010-A1 USE OF LONG CHAIN AMINES AND DIFUNCTIONAL COMPOUNDS AS TRACERS BAKER HUGHES INCORPORATED (US) 2015-12-31 US disclosed
US-8383725-B2 Polyester based degradable materials and implantable biomedical articles formed therefrom THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-02-26 US disclosed
US-20120027719-A1 Polyester Based Degradable Materials and Implantable Biomedical Articles Formed Therefrom NATIONAL SCIENCE FOUNDATION 2012-02-02 US disclosed
US-8013061-B2 Polyester based degradable materials and implantable biomedical articles formed therefrom THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-09-06 US disclosed
US-20090221781-A1 POLYESTER BASED DEGRADABLE MATERIALS AND IMPLANTABLE BIOMEDICAL ARTICLES FORMED THEREFROM NATIONAL SCIENCE FOUNDATION 2009-09-03 US disclosed
WO-2007103346-A2 POLYESTER BASED DEGRADABLE COMPOSITION AND IMPLANTABLE BIOMEDICAL ARTICLES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2007-09-13 WO disclosed
EP-0729993-A1 Process for the production of polyesters using enzymes and supercritical fluids Bayer Corporation (US) 1996-09-04 EP disclosed
US-5478910-A Molecular weight control by varying pressure BAYER CORPORATION (US) 1995-12-26 US disclosed
US-5147791-A Reacting diester and dialcohol in presence of enzyme catalyst;enantiomorphs UNIVERSITY OF NEW MEXICO (US) 1992-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120027719-A1 Polyester Based Degradable Materials and Implantable Biomedical Articles Formed Therefrom HPD, ACMSD, B2M DGKA 482/4885PAM 362/4885CYP1A2 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.