SCHEMBL10112866

SCHEMBL10112866

O=C(c1cc(Cl)ccc1Cl)c1ccnc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.47
ACLY P53396 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
HTT P42858 1/20 0.44
PABPC1 P11940 1/20 0.44
EIF4H Q15056 1/20 0.44
ALDH1A1 P00352 2/20 0.44
TP53 P04637 1/20 0.44
KMT2A Q03164 2/20 0.42
RORB Q92753 1/20 0.42
FADS1 O60427 1/20 0.42
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CTSV O60911 1/20 0.41
CTSL P07711 1/20 0.41
CTSS P25774 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23193358 0.83 NCF1 (0.50) NPC1RAB9ATP53SMN1; SMN2
SCHEMBL9033128 0.80 NPC1 (0.50) NPC1RAB9AHTTPABPC1EIF4H
SCHEMBL10084179 0.78 KDR (0.52) RAB9A
SCHEMBL7033164 0.77 MAPT (0.55) NPC1RAB9AHTTALDH1A1KMT2A
SCHEMBL7033159 0.77 MAPT (0.55) NPC1RAB9AHTTALDH1A1KMT2A
SCHEMBL8160214 0.76 ALDH1A1 (0.71) RECQLRAB9AALDH1A1TP53LMNA
SCHEMBL5591940 0.75 KDM4E (0.50) HTTALDH1A1KMT2ALMNASMN1; SMN2
SCHEMBL11842389 0.74 RECQL (0.77) RECQLALDH1A1TP53RORBLMNA
SCHEMBL7577962 0.74 TGFBR1 (0.50) NPC1RAB9AALDH1A1KMT2AFADS1
SCHEMBL17151063 0.73 ALDH1A1 (0.48) HTTALDH1A1KMT2AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed