Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753442 | 0.87 | KMT2A (0.58) | KMT2ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8590217 | 0.85 | MLYCD (0.70) | KMT2ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL14880133 | 0.85 | ALOX15 (0.68) | KMT2ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8574836 | 0.85 | HPGD (0.66) | KMT2ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL13164723 | 0.84 | HPGD (0.64) | KMT2ARAB9ASMN1; SMN2HPGDPARP10 | |
| SCHEMBL4719057 | 0.83 | CA1 (0.65) | KMT2ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2104776 | 0.83 | KMT2A (0.61) | KMT2ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8330051 | 0.82 | CA1 (0.66) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2408272 | 0.81 | ACACB (0.55) | KMT2ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL13753315 | 0.80 | NR1H4 (0.61) | KMT2ARAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028243-A1 | PYRAZOLO PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-02-08 | — | — | WO | disclosed |
| US-20230068959-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-03-02 | — | — | US | disclosed |
| US-10988491-B2 | Degradable polymers of a cyclic silyl ether and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-27 | — | — | US | disclosed |
| US-10752611-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-10716858-B2 | Branched multi-functional macromonomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-07-21 | — | — | US | disclosed |
| US-20200055879-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-02-20 | — | — | US | disclosed |
| US-20190038751-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-02-07 | — | — | US | disclosed |
| US-10017499-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170114046-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARM INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-20140341851-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2014-11-20 | — | — | US | disclosed |
| US-20140193363-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-8673954-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8507522-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120076756-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2012-03-29 | — | — | US | disclosed |
| US-8101643-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2010-10-14 | — | — | US | disclosed |
| US-20100233122-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114046-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | KMT2A 1865/4885RAB9A 3679/4885NPC1 159/4885 |
| US-20120076756-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | KMT2A 1865/4885RAB9A 3679/4885NPC1 159/4885 |
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, SLC10A1, EIF2AK2 | KMT2A 2957/4885RAB9A 3036/4885NPC1 36/4885 |
| US-20100233122-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | KMT2A 1865/4885RAB9A 3679/4885NPC1 159/4885 |
| US-10017499-B2 | Benzimidazole derivatives | EIF2AK2, ZC3HAV1, ZC3HAV1L | KMT2A 1492/4885RAB9A 3990/4885NPC1 162/4885 |
| US-20200055879-A1 | DEGRADABLE POLYMERS OF A CYCLIC SILYL ETHER AND USES THEREOF | SI, ILK, PCNA | KMT2A 2882/4885RAB9A 3208/4885NPC1 3430/4885 |
| US-20190038751-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND USES THEREOF | MSN, NEDD8, CAD | KMT2A 1550/4885RAB9A 2676/4885NPC1 1615/4885 |
| US-10988491-B2 | Degradable polymers of a cyclic silyl ether and uses thereof | SI, ILK, PCNA | KMT2A 2882/4885RAB9A 3208/4885NPC1 3430/4885 |
| US-20140193363-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | KMT2A 1865/4885RAB9A 3679/4885NPC1 159/4885 |
| US-10716858-B2 | Branched multi-functional macromonomers and uses thereof | MSN, NEDD8, CAD | KMT2A 1550/4885RAB9A 2676/4885NPC1 1615/4885 |
| US-20230068959-A1 | BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND RELATED POLYMERS AND USES THEREOF | MSN, CAD, NEDD8 | KMT2A 1679/4885RAB9A 3373/4885NPC1 2708/4885 |
| US-20140341851-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | EIF2AK2, ZC3HAV1, HAVCR2 | KMT2A 1865/4885RAB9A 3679/4885NPC1 159/4885 |
| US-10752611-B2 | Benzimidazole derivatives | EIF2AK2, ZC3HAV1, ZC3HAV1L | KMT2A 1492/4885RAB9A 3990/4885NPC1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.