Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011496 | 0.81 | HSD11B1 (0.38) | GAAALDH1A1CYP2D6ALKBH5HSD11B1 | |
| SCHEMBL1012740 | 0.80 | ELANE (0.37) | CYP2D6OPRM1OPRK1OPRL1ALKBH5 | |
| SCHEMBL1010268 | 0.78 | CHRM2 (0.36) | GAAL3MBTL1ALDH1A1OPRK1ALKBH5 | |
| SCHEMBL1011462 | 0.76 | ABL1 (0.40) | ALDH1A1OPRM1CCR5 | |
| SCHEMBL1012463 | 0.73 | FKBP1A (0.45) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1012462 | 0.67 | HSD11B1 (0.40) | GAAALDH1A1CYP2D6OPRM1HSD11B1 | |
| SCHEMBL11099774 | 0.65 | GRM6 (0.40) | GAACYP2D6OPRM1OPRK1HSD11B1 | |
| SCHEMBL7247464 | 0.65 | SLC6A4 (0.43) | L3MBTL1OPRM1OPRK1CYP3A4CYP2C19 | |
| SCHEMBL1012334 | 0.64 | SLC6A4 (0.44) | L3MBTL1 | |
| SCHEMBL24832496 | 0.64 | GRM6 (0.47) | ACEL3MBTL1ALDH1A1CYP2D6HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |