Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012740 | 0.89 | ELANE (0.37) | ABL1RIN1LMNAMEN1KMT2A | |
| SCHEMBL1010268 | 0.85 | CHRM2 (0.36) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL1011496 | 0.79 | HSD11B1 (0.38) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1012336 | 0.76 | ACE (0.37) | ALDH1A1CCR5OPRM1 | |
| SCHEMBL1012463 | 0.70 | FKBP1A (0.45) | ALDH1A1MAPTHPGDHSD17B10KMT2A | |
| SCHEMBL1012462 | 0.65 | HSD11B1 (0.40) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| SCHEMBL1011459 | 0.64 | SLC6A4 (0.42) | — | |
| SCHEMBL11099774 | 0.63 | GRM6 (0.40) | LMNAMEN1KMT2AOPRM1SIGMAR1 | |
| SCHEMBL7247464 | 0.63 | SLC6A4 (0.43) | KMT2AOPRM1 | |
| SCHEMBL1012738 | 0.60 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2APKMSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |