Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012740 | 0.89 | ELANE (0.37) | ALKBH5OPRK1LMNAPOLBNPSR1 | |
| SCHEMBL1011462 | 0.85 | ABL1 (0.40) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL1011496 | 0.81 | HSD11B1 (0.38) | ALKBH5S1PR1S1PR5ALDH1A1LMNA | |
| SCHEMBL1012336 | 0.78 | ACE (0.37) | ALKBH5ALDH1A1OPRK1L3MBTL1GAA | |
| SCHEMBL1012463 | 0.72 | FKBP1A (0.45) | ALDH1A1NPSR1KMT2A | |
| SCHEMBL1012858 | 0.71 | SMN1; SMN2 (0.43) | GAA | |
| SCHEMBL7247464 | 0.67 | SLC6A4 (0.43) | CHRM2CHRM3OPRK1L3MBTL1TSHR | |
| SCHEMBL1012462 | 0.66 | HSD11B1 (0.40) | CHRM2CHRM3ALDH1A1GAAMEN1 | |
| SCHEMBL11099774 | 0.64 | GRM6 (0.40) | S1PR1S1PR5OPRK1LMNAGRM6 | |
| SCHEMBL21631826 | 0.62 | OPRM1 (0.36) | CHRM2CHRM3ALDH1A1OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |