Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010268 | 0.89 | CHRM2 (0.36) | LMNANPSR1ALKBH5MEN1POLB | |
| SCHEMBL1011462 | 0.89 | ABL1 (0.40) | OPRM1SIGMAR1LMNAABL1RIN1 | |
| SCHEMBL1011496 | 0.82 | HSD11B1 (0.38) | ELANELMNAALKBH5CYP2D6HSD11B1 | |
| SCHEMBL1012336 | 0.80 | ACE (0.37) | OPRM1ALKBH5CYP2D6HSD11B1OPRK1 | |
| SCHEMBL1012463 | 0.74 | FKBP1A (0.45) | NPSR1KMT2A | |
| SCHEMBL1012462 | 0.68 | HSD11B1 (0.40) | ELANEOPRM1SIGMAR1CYP2D6HSD11B1 | |
| SCHEMBL7247464 | 0.66 | SLC6A4 (0.43) | OPRM1KMT2AOPRK1 | |
| SCHEMBL11099774 | 0.66 | GRM6 (0.40) | OPRM1SIGMAR1LMNACYP2D6HSD11B1 | |
| SCHEMBL1011495 | 0.64 | SLC6A4 (0.54) | KMT2A | |
| SCHEMBL1015012 | 0.64 | SLC6A4 (0.54) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |