Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012463 | 0.88 | FKBP1A (0.45) | ALDH1A1CYP2C9KMT2A | |
| SCHEMBL1012740 | 0.82 | ELANE (0.37) | HSD11B1ELANEALKBH5CYP2D6MEN1 | |
| SCHEMBL1012336 | 0.81 | ACE (0.37) | HSD11B1ALDH1A1GAACYP3A4ALKBH5 | |
| SCHEMBL1010268 | 0.81 | CHRM2 (0.36) | ALDH1A1GAAALKBH5TSHRMEN1 | |
| SCHEMBL1011462 | 0.79 | ABL1 (0.40) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11099774 | 0.79 | GRM6 (0.40) | HSD11B1GAACYP2D6MEN1LMNA | |
| SCHEMBL1012462 | 0.72 | HSD11B1 (0.40) | HSD11B1ALDH1A1GAAELANECYP3A4 | |
| SCHEMBL17311985 | 0.68 | NR1H2 (0.40) | HSD11B1ALDH1A1CYP2D6MEN1LMNA | |
| SCHEMBL7247464 | 0.68 | SLC6A4 (0.43) | CYP3A4TSHRKMT2A | |
| SCHEMBL11093783 | 0.65 | CCR2 (0.41) | HSD11B1GAAELANECYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |